Contents

Current Topics in Medicinal Chemistry, Volume 8 - Number 13

Editorial [Hot topic: Medicinal Chemistry Strategies to Minimize hERG Channel Effects 23 May (Guest Editor:Mark T. Bilodeau)]

, 8(13): 1101

Mark T. Bilodeau


DOI: 10.2174/156802608785700025




The hERG Channel and Risk of Drug-Acquired Cardiac Arrhythmia: An Overview

, 8(13): 1102 - 1112

Armando A. Lagrutta, Elena S. Trepakova and Joseph J. Salata


DOI: 10.2174/156802608785700016




Ligand Structural Aspects of hERG Channel Blockade

, 8(13): 1113 - 1127

Alex M. Aronov


DOI: 10.2174/156802608785700061




The Impact of IKr Blockade on Medicinal Chemistry Programs

, 8(13): 1128 - 1139

Ian M. Bell and Mark T. Bilodeau


DOI: 10.2174/156802608785700034




Overcoming hERG Affinity in the Discovery of Maraviroc; A CCR5 Antagonist for the Treatment of HIV

, 8(13): 1140 - 1151

David A. Price, Duncan Armour, Marcel de Groot, Derek Leishman, Carolyn Napier, Manos Perros, Blanda L. Stammen and Anthony Wood


DOI: 10.2174/156802608785700007




Lead Optimization of Melanin Concentrating Hormone Receptor 1 Antagonists with low hERG Channel Activity

, 8(13): 1152 - 1157

Andrew S. Judd, Andrew J. Souers and Philip R. Kym


DOI: 10.2174/156802608785700052




Molecule of the Month

, 8(13): 1158

Craig W. Lindsley


DOI: 10.2174/156802608785700043




Webmaster Contact: info@benthamscience.org
Copyright © 2018 Bentham Science