Contents

Current Topics in Medicinal Chemistry, Volume 7 - Number 8

Editorial [Hot Topic: Phospholipase Inhibition: Medicinal Chemistry and Therapeutic Potential of PLA2 Inhibitors (Guest Editor: Dr. K.S. Rangappa)]

, 7(8): 741 - 742

K. S. Rangappa


DOI: 10.2174/156802607780487641




Snake Venom Phospholipase A2 Inhibitors: Medicinal Chemistry and Therapeutic Potential

, 7(8): 743 - 756

Silvana Marcussi, Carolina D. Sant'Ana, Clayton Z. Oliveira, Aristides Quintero Rueda, Danilo L. Menaldo, Rene O. Beleboni, Rodrigo G. Stabeli, Jose R. Giglio, Marcos R. M. Fontes and Andreimar M. Soares


DOI: 10.2174/156802607780487614




Structural Elements of Ligand Recognition Site in Secretory Phospholipase A2 and Structure-Based Design of Specific Inhibitors

, 7(8): 757 - 764

Nagendra Singh, Rishi K. Somvanshi, Sujata Sharma, Sharmistha Dey, Punit Kaur and Tej P. Singh


DOI: 10.2174/156802607780487669




PLA2 Mediated Arachidonate Free Radicals: PLA2 Inhibition and Neutralization of Free Radicals by Anti-Oxidants – A New Role as Anti-Inflammatory Molecule

, 7(8): 765 - 777

B. L. Nanda, A. Nataraju, R. Rajesh, K. S. Rangappa, M. A. Shekar and B. S. Vishwanath


DOI: 10.2174/156802607780487623




Structural Biology of Recombinant Bovine Pancreatic Phospholipase A2 and its Inhibitor Complexes

, 7(8): 779 - 785

K. Sekar


DOI: 10.2174/156802607780487632




Chemistry and Structural Evaluation of Different Phospholipase A2 Inhibitors in Arachidonic Acid Pathway Mediated Inflammation and Snake Venom Toxicity

, 7(8): 787 - 800

J. N. Narendra Sharath Chandra, K. C. Ponnappa, C. T. Sadashiva, B. S. Priya, B. L. Nanda, T. Veerabasappa Gowda, B. S. Vishwanath and K. S. Rangappa


DOI: 10.2174/156802607780487678




Group IIA Secretory PLA2 Inhibition by Ursolic Acid: A Potent Anti-Inflammatory Molecule

, 7(8): 801 - 809

A. Nataraj, C. D. Raghavendra Gowda, R. Rajesh and B. S. Vishwanath


DOI: 10.2174/156802607780487696




Synthesis and Evaluation of Tricyclic Dipyrido Diazepinone Derivatives as Inhibitors of Secretory Phospholipase A2 with Anti-Inflammatory Activity

, 7(8): 811 - 820

N. R. Thimmegowda, K. K. Dharmappa, C. S. Ananda kumar, M. P. Sadashiva, A. D. Sathish, B. L. Nanda, B. S. Vishwanath and K. S. Rangappa


DOI: 10.2174/156802607780487650




Molecule of the Month

, 7(8): 821

Kari Anne Myers


DOI: 10.2174/156802607780487687




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