Contents

Current Topics in Medicinal Chemistry, Volume 7 - Number 7

Editorial [Hot Topic: Modified Nucleic Acid Substructures in Medicinal Chemistry and Drug Development (Guest Editor: Dr. Vaijayanti A. Kumar)]

, 7(7): 639

Vaijayanti A. Kumar


DOI: 10.2174/156802607780487731




2-Modified Oligonucleotides for Antisense Therapeutics

, 7(7): 641 - 649

Thazha P. Prakash and Balkrishen Bhat


DOI: 10.2174/156802607780487713




Morpholino, siRNA, and S-DNA Compared: Impact of Structure and Mechanism of Action on Off-Target Effects and Sequence Specificity

, 7(7): 651 - 660

James E. Summerton


DOI: 10.2174/156802607780487740




True Antisense Oligonucleotides with Modified Nucleotides Restricted in the Nconformation

, 7(7): 661 - 665

Makoto Koizumi


DOI: 10.2174/156802607780487768




Nucleobase Modifications in Peptide Nucleic Acids

, 7(7): 667 - 679

Filip Wojciechowski and Robert H. E. Hudson


DOI: 10.2174/156802607780487795




Peptide Nucleic Acids with a Structurally Biased Backbone: Effects of Conformational Constraints and Stereochemistry

, 7(7): 681 - 694

Roberto Corradini, Stefano Sforza, Tullia Tedeschi, Filbert Totsingan and Rosangela Marchelli


DOI: 10.2174/156802607780487759




P-Chiral Oligonucleotides in Biological Recognition Processes

, 7(7): 695 - 713

Piotr Guga


DOI: 10.2174/156802607780487786




Structure-Editing of Nucleic Acids for Selective Targeting of RNA

, 7(7): 715 - 726

Vaijayanti A. Kumar and K. N. Ganesh


DOI: 10.2174/156802607780487722




Chemical Modifications to Improve the Cellular Uptake of Oligonucleotides

, 7(7): 727 - 737

Francoise Debart, Said Abes, Gaelle Deglane, Hong M. Moulton, Philippe Clair, Michael J. Gait, Jean-Jacques Vasseur and Bernard Lebleu


DOI: 10.2174/156802607780487704




Molecule of the Month

, 7(7): 739

Craig W. Lindsley


DOI: 10.2174/156802607780487777




Webmaster Contact: info@benthamscience.org
Copyright © 2018 Bentham Science