Contents

Current Topics in Medicinal Chemistry, Volume 7 - Number 6

Editorial [ Hot Topic: DPP-IV as a Target in Medicinal Chemistry and Drug Discovery (Guest Editor: Dr. Jens-Uwe Peters) ]

, 7(6): 545

Jens-Uwe Peters


DOI: 10.2174/156802607780091037




Dipeptidyl Peptidase IV Inhibitors: The Next Generation of New Promising Therapies for the Management of Type 2 Diabetes

, 7(6): 547 - 555

Elena Sebokova, Andreas D. Christ, Markus Boehringer and Jacques Mizrahi


DOI: 10.2174/156802607780091019




Discovery of JANUVIA TM (Sitagliptin), a Selective Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type2 Diabetes.

, 7(6): 557 - 568

Nancy A. Thornberry and Ann E. Weber


DOI: 10.2174/156802607780091028




Aromatic Heterocycle-Based DPP-IV Inhibitors: Xanthines and Related Structural Types.

, 7(6): 569 - 578

Bruce G. Szczepankiewicz and Ravi Kurukulasuriya


DOI: 10.2174/156802607780091073




11 Years of Cyanopyrrolidines as DPP-IV Inhibitors

, 7(6): 579 - 595

Jens-Uwe Peters


DOI: 10.2174/156802607780091000




Azetidine-Based Inhibitors of Dipeptidyl Peptidase IV (DPP IV)

, 7(6): 597 - 608

Dana Ferraris, Sergei Belyakov, Weixing Li, Eddie Oliver, Yao-Sen Ko, David Calvin, Susan Lautar, Bert Thomas and Camilo Rojas


DOI: 10.2174/156802607780090993




Molecular Recognition of Ligands in Dipeptidyl Peptidase IV

, 7(6): 609 - 620

Bernd Kuhn, Michael Hennig and Patrizio Mattei


DOI: 10.2174/156802607780091064




Prolyl Peptidases Related to Dipeptidyl Peptidase IV: Potential of Specific Inhibitors in Drug Discovery.

, 7(6): 621 - 635

Pieter Van der Veken, Achiel Haemers and Koen Augustyns


DOI: 10.2174/156802607780091046




Molecule of the Month

, 7(6): 637

Craig W. Lindsley


DOI: 10.2174/156802607780091055




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