Contents

Current Topics in Medicinal Chemistry, Volume 7 - Number 16

Editorial [Hot Topic: Fragment-Based Drug Discovery Approaches (Guest Editors: Jeffrey Albert and Judd Berman)]

, 7(16): 1543

Jeffrey Albert and Judd Berman


DOI: 10.2174/156802607782341127




Fragment-Based Drug Discovery: What has it Achieved so Far?

, 7(16): 1544 - 1567

Alexander A. Alex and Maria M. Flocco


DOI: 10.2174/156802607782341082




The SeeDs Approach: Integrating Fragments into Drug Discovery

, 7(16): 1568 - 1581

Roderick E. Hubbard, Ben Davis, Ijen Chen and Martin J. Drysdale


DOI: 10.2174/156802607782341109




Fragment Based Drug Discovery Using Fluorescence Correlation Spectroscopy Techniques: Challenges and Solutions

, 7(16): 1582 - 1591

T. Hesterkamp, J. Barker, A. Davenport and M. Whittaker


DOI: 10.2174/156802607782341064




Practical Aspects of NMR-based Fragment Discovery

, 7(16): 1592 - 1599

Edward R. Zartler and Huaping Mo


DOI: 10.2174/156802607782341055




An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZenecas Drug Discovery Programmes

, 7(16): 1600 - 1629

Jeffrey S. Albert, Niklas Blomberg, Alexander L. Breeze, Alastair J. H. Brown, Jeremy N. Burrows, Philip D. Edwards, Rutger H. A. Folmer, Stefan Geschwindner, Ed J. Griffen, Peter W. Kenny, Thorsten Nowak, Lise-Lotte Olsson, Hitesh Sanganee and Adam B. Shapiro


DOI: 10.2174/156802607782341091




SPR-based Fragment Screening: Advantages and Applications

, 7(16): 1630 - 1642

T. Neumann, H-D. Junker, K. Schmidt and R. Sekul


DOI: 10.2174/156802607782341073




Molecule of the Month

, 7(16): 1643

Julie D. Bolinger and Craig W. Lindsley


DOI: 10.2174/156802607782341118




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