Contents

Current Topics in Medicinal Chemistry, Volume 6 - Number 7

Editorial [Hot Topic: NMDA Receptors as Targets in Medicinal Chemistry (Guest Editor: Dr. William Metz)]

, 6(7): 649 - 650

William A. Metz


DOI: 10.2174/156802606776894492




Glycine/NMDA Receptor Antagonists as Potential CNS Therapeutic Agents: ACEA-1021 and Related Compounds

, 6(7): 651 - 662

Sui X. Cai


DOI: 10.2174/156802606776894465




NMDA Receptors are not Alone: Dynamic Regulation of NMDA Receptor Structure and Function by Neuregulins and Transient Cholesterol-Rich Membrane Domains Leads to Disease-Specific Nuances of Glutamate- Signalling

, 6(7): 663 - 686

Andre Schrattenholz and Vukic Soskic


DOI: 10.2174/156802606776894519




NR2B Selective NMDA Antagonists: The Evolution of the Ifenprodil-Type Pharmacophore

, 6(7): 687 - 695

Istvan Borza and Gyorgy Domany


DOI: 10.2174/156802606776894456




Recent Advances in the Development of NR2B Subtype-Selective NMDA Receptor Antagonists

, 6(7): 697 - 709

Mark E. Layton, Michael J. Kelly III and Kevin J. Rodzinak


DOI: 10.2174/156802606776894447




Targeting PDZ Domain Proteins for Treating NMDA Receptor-Mediated Excitotoxicity

, 6(7): 711 - 721

Wenyu Wen, Wenning Wang and Mingjie Zhang


DOI: 10.2174/156802606776894474




Relationships Between the Structure of Dexoxadrol and Etoxadrol Analogues and their NMDA Receptor Affinity

, 6(7): 723 - 732

Michael Sax and Bernhard Wunsch


DOI: 10.2174/156802606776894483




Tricyclic Quinoxalinediones, Aza-kynurenic Acids, and Indole-2- Carboxylic Acids as In Vivo Active NMDA-Glycine Antagonists

, 6(7): 733 - 745

Ryu Nagata, Seiji Katayama, Ken-ichi Ohtani, Hiroyasu Tanaka and Kozo Shimago


DOI: 10.2174/156802606776894500




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