Contents

Current Topics in Medicinal Chemistry, Volume 5 - Number 9

Editorial [Hot Topic: Metabotropic Glutamate Receptors: Medicinal Chemistry and Therapeutic Implications (Guest Editor: Craig W. Lindsley)]

, 5(9): 823

Craig W. Lindsley


DOI: 10.2174/1568026054750308




Discovery of Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 (mGluR5)

, 5(9): 825 - 846

David L. Williams Jr. and Craig W. Lindsley


DOI: 10.2174/1568026054750290




New Therapeutic Frontiers for Metabotropic Glutamate Receptors

, 5(9): 847 - 857

Colleen M. Niswender, Carrie K. Jones and P. Jeffrey Conn


DOI: 10.2174/1568026054750254




Subtype-Selective Noncompetitive Modulators of Metabotropic Glutamate Receptor Subtype 1 (mGluR1)

, 5(9): 859 - 867

Mark E. Layton


DOI: 10.2174/1568026054750245




Positive Allosteric Modulators of the Metabotropic Glutamate Receptor Subtype 2 (mGluR2)

, 5(9): 869 - 884

Michael T. Rudd and John A. McCauley


DOI: 10.2174/1568026054750281




Targeting the Metabotropic Glutamate Receptor mGluR4 for the Treatment of Diseases of the Central Nervous System

, 5(9): 885 - 895

Michael J. Marino, J. F. Hess and Nigel Liverton


DOI: 10.2174/1568026054750263




Recent Advances in Non-Competitive mGlu5 Receptor Antagonists and their Potential Therapeutic Applications

, 5(9): 897 - 911

Abdelmalik Slassi, Methvin Isaac, Louise Edwards, Alexander Minidis, David Wensbo, Jan Mattsson, Karolina Nilsson, Patrick Raboisson, Donald McLeod, Thomas M. Stormann, Lance G. Hammerland and Edwin Johnson


DOI: 10.2174/1568026054750236




Agonists and Antagonists for Group III Metabotropic Glutamate Receptors 6, 7 and 8

, 5(9): 913 - 918

Zhi-Qiang Yang


DOI: 10.2174/1568026054750272




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