Current Topics in Medicinal Chemistry, Volume 4 - Number 14

Preface [Hot Topic: Perspective on VLA-4 Antagonists (Guest Editor: Jefferson W. Tilley)]

, 4(14): i

Jefferson W. Tilley

DOI: 10.2174/1568026043387485

The Discovery and Potential of N-Sulfonylated Dipeptide VLA-4 Antagonists

, 4(14): 1461 - 1471

William K. Hagmann

DOI: 10.2174/1568026043387557

The Identification and Optimization of Orally Efficacious, Small Molecule VLA-4 Antagonists

, 4(14): 1473 - 1484

Donna M. Huryn, Andrei W. Konradi, Susan Ashwell, Stephen B. Freedman, Louis J. Lombardo, Michael A. Pleiss, Eugene D. Thorsett, Ted Yednock and Jeffrey D. Kennedy

DOI: 10.2174/1568026043387467

Therapeutic Antagonists and the Conformational Regulation of the β2 Integrins

, 4(14): 1485 - 1495

Motomu Shimaoka and Timothy A. Springer

DOI: 10.2174/1568026043387575

Rational Design of Potent and Selective VLA-4 Inhibitors and their Utility in the Treatment of Asthma

, 4(14): 1497 - 1507

Juswinder Singh, Steve Adams, Mary Beth Carter, Hernan Cuervo, Wen-Cherng Lee, Roy R. Lobb, R. Blake Pepinsky, Russell Petter and Daniel Scott

DOI: 10.2174/1568026043387520

The Discovery of VLA-4 Antagonists

, 4(14): 1509 - 1523

Jefferson W. Tilley, Li Chen, Achyutharao Sidduri and Nader Fotouhi

DOI: 10.2174/1568026043387502

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