Contents

Current Topics in Medicinal Chemistry, Volume 4 - Number 12

Preface [Hot Topic: Bioorganic Chemical Approaches for the Design of Protease Inhibitors (Guest Editor: Dong H. Kim)]

, 4(12): i

Dong H. Kim


DOI: 10.2174/1568026043387872




Preface [Hot Topic: Bioorganic Chemical Approaches for the Design of Protease Inhibitors (Guest Editor: Dong H. Kim)]

, 4(12): i

Dong H. Kim


DOI: 10.2174/1568026043387872




Preface [Hot Topic: Matrix Metalloproteinase Inhibitors (Guest Editor: Jeremy I. Levin)]

, 4(12): ii

Jeremy I. Levin


DOI: 10.2174/1568026043387926




Preface [Hot Topic: Matrix Metalloproteinase Inhibitors (Guest Editor: Jeremy I. Levin)]

, 4(12): ii

Jeremy I. Levin


DOI: 10.2174/1568026043387926




Recent Developments in the Design of Mechanism-based and Alternate Substrate Inhibitors of Serine Proteases

, 4(12): 1203 - 1216

Jiaying Zhong and William C. Groutas


DOI: 10.2174/1568026043387971




Chemistry-based Design of Inhibitors for Carboxypeptidase A

, 4(12): 1217 - 1226

Dong H. Kim


DOI: 10.2174/1568026043387908




Quest for Selectivity in Inhibition of Matrix Metalloproteinases

, 4(12): 1227 - 1238

Stephen Brown, Samy O. Meroueh, Rafael Fridman and Shahriar Mobashery


DOI: 10.2174/1568026043387854




Inhibitors of 3C Cysteine Proteinases from Picornaviridae

, 4(12): 1239 - 1253

Manjinder S. Lall, Rajendra P. Jain and John C. Vederas


DOI: 10.2174/1568026043387836




The Evolution of the Matrix Metalloproteinase Inhibitor Drug Discovery Program at Abbott Laboratories

, 4(12): 1255 - 1267

Carol K. Wada


DOI: 10.2174/1568026043388015




Sulfonamide-Based Acyclic and Conformationally Constrained MMP Inhibitors: From Computer-Assisted Design to Nanomolar Compounds

, 4(12): 1269 - 1287

Stephen Hanessian and Nicolas Moitessier


DOI: 10.2174/1568026043387953




The Design and Synthesis of Aryl Hydroxamic Acid Inhibitors of MMPs and TACE

, 4(12): 1289 - 1310

Jeremy I. Levin


DOI: 10.2174/1568026043387935




The Application of X-ray, NMR, and Molecular Modeling in the Design of MMP Inhibitors

, 4(12): 1311 - 1327

Thomas S. Rush III and Robert Powers


DOI: 10.2174/1568026043387999




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