Contents

Current Topics in Medicinal Chemistry, Volume 17 - Number 6

Editorial

EDITORIAL (Thematic Issue : Rexinoids)

, 17(6): 629 - 630

Carl E. Wagner, Pamela A. Marshall and Peter W. Jurutka


DOI: 10.2174/156802661706170111200835




Review Article

Natural and Structure-based RXR Ligand Scaffolds and Their Functions

, 17(6): 631 - 662

Marta Dominguez, Susana Alvarez and Angel R. de Lera


DOI: 10.2174/1568026616666160617072521





Review Article

Recent Progress in the Design and Discovery of RXR Modulators Targeting Alternate Binding Sites of the Receptor

, 17(6): 663 - 675

Ying Su, Zhiping Zeng, Ziwen Chen, Dan Xu, Weidong Zhang and Xiao-kun Zhang


DOI: 10.2174/1568026616666160617092241





Review Article

Translation of a Tissue-Selective Rexinoid, UAB30, to the Clinic for Breast Cancer Prevention

, 17(6): 676 - 695

Donald D. Muccio, Venkatram R. Atigadda, Wayne J. Brouillette, Kirby I. Bland, Helen Krontiras and Clinton J. Grubbs


DOI: 10.2174/1568026616666160617093604





Review Article

Retinoid X Receptor Ligands with Anti-Type 2 Diabetic Activity

, 17(6): 696 - 707

Ken-ichi Morishita and Hiroki Kakuta


DOI: 10.2174/1568026616666160617085545





Review Article

Rexinoids as Therapeutics for Alzheimer’s Disease: Role of APOE

, 17(6): 708 - 720

Kevin P. Koster, Conor Smith, Ana C. Valencia-Olvera, Gregory R.J. Thatcher, Leon M. Tai and Mary Jo LaDu


DOI: 10.2174/1568026616666160617090227





Review Article

Rexinoids for Prevention and Treatment of Cancer: Opportunities and Challenges

, 17(6): 721 - 730

Karen T. Liby and Michael B. Sporn


DOI: 10.2174/1568026616666160617090702





Review Article

Computer Simulations of the Retinoid X Receptor: Conformational Dynamics and Allosteric Networks

, 17(6): 731 - 741

Arjan van der Vaart, Alexander Lorkowski, Ning Ma and Geoffrey M. Gray


DOI: 10.2174/1568026616666160617084745





Review Article

Retinoid X Receptor Selective Agonists and their Synthetic Methods

, 17(6): 742 - 767

Carl E. Wagner, Peter W. Jurutka, Pamela A. Marshall and Michael C. Heck


DOI: 10.2174/1568026616666160617091559





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