Current Topics in Medicinal Chemistry, Volume 17 - Number 24


Editorial: Metabolomics

, 17(24): 2715

Gary W. Caldwell

DOI: 10.2174/156802661724170828093315

Review Article

Can Untargeted Metabolomics Be Utilized in Drug Discovery/Development?

, 17(24): 2716 - 2739

Gary W. Caldwell and Gregory C. Leo

DOI: 10.2174/1568026617666170707130032

Review Article

Metabolomics Applications in Precision Medicine: An Oncological Perspective

, 17(24): 2740 - 2751

Leonor Puchades-Carrasco and Antonio Pineda- Lucena

DOI: 10.2174/1568026617666170707120034

Review Article

Molecular Determinants of Chronic Liver Disease as Studied by NMR-Metabolomics

, 17(24): 2752 - 2766

Nieves Embade and Oscar Millet

DOI: 10.2174/1568026617666170707124539

Review Article

Evaluation of Temporal Changes in Urine-based Metabolomic and Kidney Injury Markers to Detect Compound Induced Acute Kidney Tubular Toxicity in Beagle Dogs

, 17(24): 2767 - 2780

M. P. Wagoner, Y. Yang, J. E. McDuffie, M. Klapczynski, W. Buck, L Cheatham, D. Eisinger, F. Sace, K. M. Lynch , M. Sonee, J-Y. Ma, Y. Chen, K. Marshall, M. Damour , L. Stephen, Y. P. Dragan, J. Fikes, S. Snook and L. B. Kinter

DOI: 10.2174/1568026617666170713172331

Research Article

LC/MS/MS Profiling of Tissue Oxysterols and its Application in Dextran Sodium Sulphate Induced Mouse Colitis Models

, 17(24): 2781 - 2790

Jiejun Wu, J.Eric McDuffie, Jiao Song, Michael C. Harris, Holly Raymond, Yafei Chen, Leslie Nguyen, Steven Nguyen, Justin Kanerva, Heather M. McAllister, Xiaohu Deng, Neelakandha Mani, Changlu Liu and Siquan Sun

DOI: 10.2174/1568026617666170713165519

Research Article

An In Vivo Rat α-D-glucose Stable Isotope Homeostasis Drug Discovery Screen: A Targeted Metabolomics Approach

, 17(24): 2791 - 2804

Gary W. Caldwell and Wensheng Lang

DOI: 10.2174/1568026617666170707130401

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