Contents

Current Topics in Medicinal Chemistry, Volume 16 - Number 19

Editorial

Editorial (Thematic Issue: Drug Reprofiling: An Alternative Path to Drug Discovery)

, 16(19): 2067 - 2068

C. S. Ramaa


DOI: 10.2174/156802661619160530204415




Computational Drug Repositioning: A Lateral Approach to Traditional Drug Discovery?

, 16(19): 2069 - 2077

Niteshkumar U. Sahu and Prashant S. Kharkar


DOI: 10.2174/1568026616666160216153249





The Importance of Bioactivation in Computer-Guided Drug Repositioning. Why the Parent Drug is Not Always Enough

, 16(19): 2078 - 2087

Alan Talevi


DOI: 10.2174/1568026616666160216155043





The Repurposing of Old Drugs or Unsuccessful Lead Compounds by in Silico Approaches: New Advances and Perspectives

, 16(19): 2088 - 2106

Annamaria Martorana, Ugo Perricone and Antonino Lauria


DOI: 10.2174/1568026616666160216153457





Scaffold Repurposing of Old Drugs Towards New Cancer Drug Discovery

, 16(19): 2107 - 2114

Haijun Chen, Jianlei Wu, Yu Gao, Haiying Chen and Jia Zhou


DOI: 10.2174/1568026616666160216155556





Reprofiling of Troglitazone Towards More Active and Less Toxic Derivatives: A New Hope for Cancer Treatment?

, 16(19): 2115 - 2124

Sabine Mazerbourg, Sandra Kuntz, Isabelle Grillier-Vuissoz, Audrey Berthe, Marine Geoffroy, Stéphane Flament, Andrea Bordessa and Michel Boisbrun


DOI: 10.2174/1568026616666160216153036





Repositioning of DHFR Inhibitors

, 16(19): 2125 - 2143

Arundhati Chandrashekhar Lele, Deepak Amarnath Mishra, Tengku Karmila Kamil, Sanjib Bhakta and Mariam Sohel Degani


DOI: 10.2174/1568026616666160216152540





Revisiting Non-Cancer Drugs for Cancer Therapy

, 16(19): 2144 - 2155

Eun Ju Yang, Changjie Wu, Yifan Liu, Junfang Lv and Joong Sup Shim


DOI: 10.2174/1568026616666160216154441





An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs

, 16(19): 2156 - 2168

Deepak Bhattarai, Sarbijt Singh, Yerin Jang, Seung Hyeon Han, Kyeong Lee and Yongseok Choi


DOI: 10.2174/1568026616666160216153618





Repurposing Drugs for Cancer Prevention

, 16(19): 2169 - 2178

Daniel K. Lee and Eva Szabo


DOI: 10.2174/1568026616666160216154946





Irreversible LSD1 Inhibitors: Application of Tranylcypromine and Its Derivatives in Cancer Treatment

, 16(19): 2179 - 2188

Yi C. Zheng, Bin Yu, Guo Z. Jiang, Xue J. Feng, Peng X. He, Xiao Y. Chu, Wen Zhao and Hong M. Liu


DOI: 10.2174/1568026616666160216154042





Repositioning of Drugs in Cardiometabolic Disorders: Importance and Current Scenario

, 16(19): 2189 - 2200

Parmeshwar B. Katare and Sanjay K. Banerjee


DOI: 10.2174/1568026616666160216152138





Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option

, 16(19): 2201 - 2222

María Laura Sbaraglini, María Cristina Vanrell, Carolina Leticia Bellera, Gustavo Benaim, Carolina Carrillo, Alan Talevi and Patricia Silvia Romano


DOI: 10.2174/1568026616666160216154309





Metformin - The Drug for the Treatment of Autoimmune Diseases; A New Use of a Known Anti-Diabetic Drug

, 16(19): 2223 - 2230

Malgorzata Tomczynska, Michal Bijak and Joanna Saluk


DOI: 10.2174/1568026616666160216152324





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