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Contents

Current Topics in Medicinal Chemistry, Volume 16 - Number 13


Advances in the Development of Class I Phosphoinositide 3-Kinase (PI3K) Inhibitors

, 16(13): 1413 - 1426

Dima A. Sabbah, Jian Hu and Haizhen A. Zhong


DOI: 10.2174/1568026615666150915115823



Targeting the Atypical Chemokine Receptor ACKR3/CXCR7: Phase 1 - Phage Display Peptide Identification and Characterization

, 16(13): 1427 - 1440

R.D. Vestal, D.R. LaJeunesse and E.W. Taylor


DOI: 10.2174/1568026615666150915120037



Drug Design Targeting the CXCR4/CXCR7/CXCL12 Pathway

, 16(13): 1441 - 1451

Dongsheng Xu, Rongshi Li, Jianguo Wu, Li Jiang and Haizhen A. Zhong


DOI: 10.2174/1568026615666150915120218



Cheminfomatic-based Drug Discovery of Human Tyrosine Kinase Inhibitors

, 16(13): 1452 - 1462

Terry-Elinor Reid, Joseph M. Fortunak, Anthony Wutoh and Xiang Simon Wang


DOI: 10.2174/1568026615666150915120814




Methionine AminoPeptidase Type-2 Inhibitors Targeting Angiogenesis

, 16(13): 1478 - 1488

Tedman Ehlers, Scott Furness, Thomas Philip Robinson, Haizhen A. Zhong, David Goldsmith, Jack Aribser and J. Phillip Bowen


DOI: 10.2174/1568026615666150915121204



G Protein Coupled Receptors And Structure-Based Advances

, 16(13): 1489 - 1505

Maria Kontoyianni


DOI: 10.2174/1568026615666150915121324



Development of Trypsin-Like Serine Protease Inhibitors as Therapeutic Agents: Opportunities, Challenges, and their Unique Structure-Based Rationales

, 16(13): 1506 - 1529

Guyan Liang and J. Phillip Bowen


DOI: 10.2174/1568026615666150915121447



Cellular Selenoprotein mRNA Tethering via Antisense Interactions with Ebola and HIV-1 mRNAs May Impact Host Selenium Biochemistry

, 16(13): 1530 - 1535

Ethan Will Taylor, Jan A. Ruzicka, Lakmini Premadasa and Lijun Zhao


DOI: 10.2174/1568026615666150915121633




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