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Contents

Current Topics in Medicinal Chemistry, Volume 16 - Number 10


Editorial


Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41

, 16(10): 1074 - 1090

Lu Lu, Fei Yu, Lifeng Cai, Asim K. Debnath and Shibo Jiang


DOI: 10.2174/1568026615666150901114527



Molecular Gymnastics: Mechanisms of HIV-1 Resistance to CCR5 Antagonists and Impact on Virus Phenotypes

, 16(10): 1091 - 1106

Michael Roche, Katharina Borm, Jacqueline K. Flynn, Sharon R. Lewin, Melissa J. Churchill and Paul R. Gorry


DOI: 10.2174/1568026615666150901114724



Contemporary HIV Vaccines: Tissue Resident T-Cells and Strategies to Prevent Mucosal Infection

, 16(10): 1107 - 1117

Hyon-Xhi Tan, Stephen J. Kent and Robert De Rose


DOI: 10.2174/1568026615666150901114920



Current Concepts for the IND-Directed Development of Microbicide Products to Prevent the Sexual Transmission of HIV

, 16(10): 1118 - 1134

Karen W. Buckheit, Christian Furlan-Freguia, Anthony S. Ham and Robert W. Buckheit


DOI: 10.2174/1568026615666150901113939



Fragment Based Strategies for Discovery of Novel HIV-1 Reverse Transcriptase and Integrase Inhibitors

, 16(10): 1135 - 1153

Catherine F. Latham, Jennifer La, Ricky N. Tinetti, David K. Chalmers and Gilda Tachedjian


DOI: 10.2174/1568026615666150901114329




Targeting Virus-host Interactions of HIV Replication

, 16(10): 1167 - 1190

Caroline Weydert, Jan De Rijck, Frauke Christ and Zeger Debyser


DOI: 10.2174/1568026615666150901115106





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