Current Topics in Medicinal Chemistry, Volume 15 - Number 21


Editorial (Thematic Issue: Current Advances in Biochemistry, Medicinal Chemistry and Drug Development Strategies for Age-Related Neurodegenerative Diseases)

, 15(21): 2115

Sandro Arguelles-Castilla

DOI: 10.2174/1568026615999150731113537

Longevity Pathways (mTOR, SIRT, Insulin/IGF-1) as Key Modulatory Targets on Aging and Neurodegeneration

, 15(21): 2116 - 2138

Caio Henrique Mazucanti, Joao Victor Cabral-Costa, Andrea Rodrigues Vasconcelos, Diana Zukas Andreotti, Cristoforo Scavone and Elisa Mitiko Kawamoto

DOI: 10.2174/1568026615666150610125715

Age-Related Neurodegeneration Prevention Through mTOR Inhibition: Potential Mechanisms and Remaining Questions

, 15(21): 2139 - 2151

Jordan B. Jahrling and Remi-Martin Laberge

DOI: 10.2174/1568026615666150610125856

Is the Modulation of Autophagy the Future in the Treatment of Neurodegenerative Diseases?

, 15(21): 2152 - 2174

Rosa Ana Gonzalez-Polo, Elisa Pizarro-Estrella, Sokhna M.S. Yakhine-Diop, Mario Rodríguez-Arribas, Ruben Gomez-Sanchez, Jose M. Bravo-San Pedro and Jose M. Fuentes

DOI: 10.2174/1568026615666150610130645

Adult Hippocampal Neurogenesis, Aging and Neurodegenerative Diseases: Possible Strategies to Prevent Cognitive Impairment

, 15(21): 2175 - 2192

Carmen Vivar

DOI: 10.2174/1568026615666150610141524

Collateral Damage: Contribution of Peripheral Inflammation to Neurodegenerative Diseases

, 15(21): 2193 - 2210

Antonio J. Herrera, Ana M. Espinosa-Oliva, Maria J. Oliva-Martin, Alejandro Carrillo-Jimenez, Jose L. Venero and Rocio M. de Pablos

DOI: 10.2174/1568026615666150610142027

The Role of Nicotinamide Phosphoribosyltransferase in Cerebral Ischemia

, 15(21): 2211 - 2221

Xinzhi Chen, Shangfeng Zhao, Yang Song, Yejie Shi, Rehana K. Leak and Guodong Cao

DOI: 10.2174/1568026615666150610142234

Neuroprotective Effects of Ginkgolide B Against Ischemic Stroke: A Review of Current Literature

, 15(21): 2222 - 2232

Seyed Mohammad Nabavi, Solomon Habtemariam, Maria Daglia, Nady Braidy, Monica Rosa Loizzo, Rosa Tundis and Seyed Fazel Nabavi

DOI: 10.2174/1568026615666150610142647

The Role of Uric Acid and Methyl Derivatives in the Prevention of Age-Related Neurodegenerative Disorders

, 15(21): 2233 - 2238

Roy G. Cutler, Simonetta Camandola, Kelli F. Malott, Maria A. Edelhauser and Mark P. Mattson

DOI: 10.2174/1568026615666150610143234

Computer Aided Drug Design Studies in the Discovery of Secondary Metabolites Targeted Against Age-Related Neurodegenerative Diseases

, 15(21): 2239 - 2252

Luciana Scotti and Marcus Tullius Scotti

DOI: 10.2174/1568026615666150610143510

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