Contents

Current Topics in Medicinal Chemistry, Volume 15 - Number 14

Graphical Abstract

Graphical Abstracts:

, 15(14): i - iii


DOI: 10.2174/156802661514150604144716




Editorial

Editorial (Thematic Issue: Potential Therapeutic Agents based on DNA Sequence- Selective Binding Substances)

, 15(14): 1291 - 1292

Leung Sheh and Michael J. Waring


DOI: 10.2174/1568026615666150414104747




Therapeutic Agents Based on DNA Sequence Specific Binding

, 15(14): 1293 - 1322

Luke Pett, John A. Hartley and Konstantinos Kiakos


DOI: 10.2174/1568026615666150413155431





Targeting Transcription Factor Binding to DNA by Competing with DNA Binders as an Approach for Controlling Gene Expression

, 15(14): 1323 - 1358

Mohamed Amine Bouhlel, Melanie Lambert and Marie-Helene David-Cordonnier


DOI: 10.2174/1568026615666150413154713





Minor-Groove Binding Agents: Rational Design of Carboxamide Bond Isosteres

, 15(14): 1359 - 1371

Chi Wi Ong and Ping Syun Yang


DOI: 10.2174/1568026615666150413155251





Structural and Functional Diversity of Estrogen Receptor Ligands

, 15(14): 1372 - 1384

Amjad Farooq


DOI: 10.2174/1568026615666150413154841





DNA Recognition by a Novel Bis-Intercalator, Potent Anticancer Drug XR5944

, 15(14): 1385 - 1397

Clement Lin and Danzhou Yang


DOI: 10.2174/1568026615666150413155608





The Interaction of DNA-Binding Ligands with Trinucleotide-Repeat DNA: Implications for Therapy and Diagnosis of Neurological Disorders

, 15(14): 1398 - 1408

Chung-ke Chang, Cyong-Ru Jhan and Ming-Hon Hou


DOI: 10.2174/1568026615666150413155030





Potential Therapeutic Advantages of Doxorubicin when Activated by Formaldehyde to Function as a DNA Adduct-Forming Agent

, 15(14): 1409 - 1422

Suzanne M. Cutts, Ada Rephaeli, Abraham Nudelman, Michal Ugarenko and Don R. Phillips


DOI: 10.2174/1568026615666150413154512





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