Contents

Current Topics in Medicinal Chemistry, Volume 14 - Number 8


Editorial


Antitrypanosomal Activity & Docking Studies of Components of Crateva adansonii DC Leaves: Novel Multifunctional Scaffolds

, 14(8): 981 - 990

Ngozichukwuka Peace Igoli, Carol Jean Clements, Rajeev Kumar Singla, John Ogbaji Igoli, Nzekwe Uche and Alexander Irvine Gray


DOI: 10.2174/1568026614666140324120006



Novel Dual Inhibitors of Nuclear Factor-Kappa B (NF-κ B) and Cyclooxygenase- 2 (COX-2): Synthesis, In Vitro Anticancer Activity and Stability Studies of Lantadene–Non Steroidal Anti-inflammatory Drug (NSAID) Conjugates

, 14(8): 991 - 1004

Sharad Kumar Suthar, Neetika Sharma, Hong Boon Lee, Khumukcham Nongalleima and Manu Sharma


DOI: 10.2174/1568026614666140324120503



QSAR Guided Semi-synthesis and In-Vitro Validation of Anticancer Activity in Ursolic Acid Derivatives

, 14(8): 1005 - 1013

Komal Kalani, Dharmendra K. Yadav, Aru Singh, Feroz Khan, M.M. Godbole and S.K. Srivastava


DOI: 10.2174/1568026614666140324121606



Antitrypanosomal Activity & Docking Studies of Isolated Constituents from the Lichen Cetraria islandica: Possibly Multifunctional Scaffolds

, 14(8): 1014 - 1021

John Ogbaji Igoli, Alexander Irvine Gray, Carol Jean Clements, Poorna Kantheti and Rajeev Kumar Singla


DOI: 10.2174/1568026614666140324122323



Modes of Action of Arjunolic Acid and Derivatives on Trypanosoma cruzi Cells

, 14(8): 1022 - 1032

Lourdes C. Souza-Neta, Diego Menezes, Milena S. Lima, Martins D. Cerqueira, Frederico G. Cruz, Dirceu Martins and Marcos A. Vannier-Santos


DOI: 10.2174/1568026614666140324122800



Structure Based Design, Synthesis, and Evaluation of Potential Inhibitors of Steroid Sulfatase

, 14(8): 1033 - 1044

E. V. Costa, E. Sousa, K. Choosang, S. Singh, J. Rocha, R .T. Lima, P. Pakkong, S. Ahmed, M.H. Vasconcelos, C.A. Montanari and M.M. Pinto


DOI: 10.2174/1568026614666140324124807



Protective Mechanism of Lignans from Phyllanthus amarus Against Galactosamine/ Lipopolysaccharide-Induced Hepatitis: An In-Vivo and In-Silico Studies

, 14(8): 1045 - 1055

Dnyaneshwar U. Bawankule, Priyanka Trivedi, Anirban Pal, Karuna Shanker, Manju Singh, Pooja Sharma, Feroz Khan, Anil K. Maurya, Ram K. Verma and Madan M.Gupta


DOI: 10.2174/1568026614666140324130047



Indole Alkaloids and Semisynthetic Indole Derivatives as Multifunctional Scaffolds Aiming the Inhibition of Enzymes Related to Neurodegenerative Diseases – A Focus on Psychotria L. Genus

, 14(8): 1056 - 1075

Luiz Carlos Klein-Junior, Carolina dos Santos Passos, Aline Pereira Moraes, Vinicius Galvao Wakui, Eduardo Luis Konrath, Alessandra Nurisso, Pierre-Alain Carrupt, Cecilia Maria Alves de Oliveira, Lucilia Kato and Amelia Teresinha Henriques


DOI: 10.2174/1568026614666140324142409



Insights on the Isolation, Biological Activity and Synthetic Protocols of Enyne Derivatives

, 14(8): 1076 - 1093

Mohamed El-Shazly, Balaji D. Barve, Michal Korinek, Jing-Ru Liou, Da-Wei Chuang, Yuan-Bin Cheng, Ming-Feng Hou, Jeh-Jeng Wang, Yang-Chang Wu and Fang-Rong Chang


DOI: 10.2174/1568026614666140324143523




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