Contents

Current Topics in Medicinal Chemistry, Volume 14 - Number 3

Editorial (Thematic Issue: Playing Well with Others! Initiating and Sustaining Successful Collaborations between Industry, Academia and Government)

, 14(3): 291 - 293

Craig J. Thomas and John C. McKew


DOI: 10.2174/1568026613666131127125351




Open Innovation Drug Discovery (OIDD): A Potential Path to Novel Therapeutic Chemical Space

, 14(3): 294 - 303

Maria Alvim-Gaston, Timothy Grese, Abdelaziz Mahoui, Alan D. Palkowitz, Marta Pineiro-Nunez and Ian Watson


DOI: 10.2174/1568026613666131127125858




A Unique Industrial – Academic Collaboration Towards the Next Generation of Schizophrenia Therapeutics

, 14(3): 304 - 312

Gregor J. Macdonald and Craig W. Lindsley


DOI: 10.2174/1568026613666131127154443




Foundation-Industry Relationships - A New Business Model Joint-Venture Philanthropy in Therapy Development

, 14(3): 313 - 318

Ronald J. Bartek


DOI: 10.2174/1568026613666131127154903




Inhibiting Caspase-6 Activation and Catalytic Activity for Neurodegenerative Diseases

, 14(3): 319 - 325

John A. Flygare and Michelle R. Arkin


DOI: 10.2174/1568026613666131126224039




Leveraging Public Private Partnerships to Innovate under Challenging Budget Times

, 14(3): 326 - 329

Lili M. Portilla and Mark L. Rohrbaugh


DOI: 10.2174/1568026613666131127155703




Collaborative Development of 2-Hydroxypropyl-β-Cyclodextrin for the Treatment of Niemann-Pick Type C1 Disease

, 14(3): 330 - 339

Elizabeth A. Ottinger, Mark L. Kao, Nuria Carrillo-Carrasco, Nicole Yanjanin, Roopa Kanakatti Shankar, Marjo Janssen, Marcus Brewster, Ilona Scott, Xin Xu, Jim Cradock, Pramod Terse, Seameen J. Dehdashti, Juan Marugan, Wei Zheng, Lili Portilla, Alan Hubbs, William J. Pavan, John Heiss, Charles H.Vite, Steven U. Walkley, Daniel S. Ory, Steven A. Silber, Forbes D. Porter, Christopher P. Austin and John C. McKew


DOI: 10.2174/1568026613666131127160118




Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS)

, 14(3): 340 - 342

David H. Drewry, Timothy M. Willson and William J. Zuercher


DOI: 10.2174/1568026613666131127160819




Editorial (Thematic Issue: Genomics and Proteomics behind Drug Design)

, 14(3): 343

Yasset Perez-Riverol and Paulo Costa Carvalho


DOI: 10.2174/1568026613666131204101110




Characterization of Protein Complexes using Targeted Proteomics

, 14(3): 344 - 350

Yassel Ramos Gomez, Sebastien Gallien, Vivian Huerta, Jan van Oostrum, Bruno Domon and Luis Javier Gonzalez


DOI: 10.2174/1568026613666131204130124




Regulation by IFN-α/IFN-γ Co-Formulation (HerberPAG®) of Genes Involved in Interferon-STAT-Pathways and Apoptosis in U87MG

, 14(3): 351 - 358

Claudia Bello, Dania Vazquez-Blomquist, Jamilet Miranda, Yanelda Garcia, Lidia Ines Novoa, Daniel Palenzuela and Iraldo Bello


DOI: 10.2174/1568026613666131204125725




Potential Correlation between Tumor Aggressiveness and Protein Expression Patterns of Nipple Aspirate Fluid (NAF) Revealed by Gel-Based Proteomic Analysis

, 14(3): 359 - 368

Giselle Villa Flor Brunoro, Andre Teixeira da Silva Ferreira, Monique Ramos de Oliveira Trugilho, Tamires Sousa de Oliveira, Luis Claudio Belo Amêndola, Jonas Perales, Richard Hemmi Valente, Claudia Vitória de Moura Gallo, Dante Pagnoncelli and Ana Gisele da Costa Neves-Ferreira


DOI: 10.2174/1568026613666131204121854




Using Mass Spectrometry-Based Peptidomics to understand the Brain and Disorders such as Parkinson’s Disease and Schizophrenia

, 14(3): 369 - 381

Cecília Cerqueira Cafe-Mendes, Emer S. Ferro, Luiz Roberto G. Britto and Daniel Martins-de-Souza


DOI: 10.2174/1568026613666131204120747




Proteome Analysis of Formalin-Fixed Paraffin-Embedded Tissues from a Primary Gastric Melanoma and its Meningeal Metastasis: A Case Report

, 14(3): 382 - 387

Juliana de S. da G. Fischer, Nathalie H. S. Canedo, Katia Maria da S. Goncalves, Leila Maria Cardao Chimelli, Monique Franca, Felipe V. Leprevost, Priscila Ferreira Aquino, Paulo C. Carvalho and Maria da Gloria C. Carvalho


DOI: 10.2174/1568026613666131204114218




A Survey of Molecular Descriptors Used in Mass Spectrometry Based Proteomics

, 14(3): 388 - 397

Enrique Audain, Aniel Sanchez, Juan Antonio Vizcaíno and Yasset Perez-Riverol


DOI: 10.2174/1568026613666131204113537




A Practical Guide to Sequencing Genomes and Transcriptomes

, 14(3): 398 - 406

Alejandro Sanchez-Flores and Cei Abreu-Goodger


DOI: 10.2174/1568026613666131204142353




Evolutionary Analysis of DNA-Protein-Coding Regions Based on a Genetic Code Cube Metric

, 14(3): 407 - 417

Robersy Sanchez


DOI: 10.2174/1568026613666131204110022




GARM: Genome Assembly, Reconciliation and Merging Pipeline

, 14(3): 418 - 424

Luz Mayela Soto-Jimenez, Karel Estrada and Alejandro Sanchez-Flores


DOI: 10.2174/1568026613666131204110628




Database Construction and Peptide Identification Strategies for Proteogenomic Studies on Sequenced Genomes

, 14(3): 425 - 434

Celine Hernandez, Patrice Waridel and Manfredo Quadroni


DOI: 10.2174/1568026613666131204105652




Bioinformatics Tools for the Functional Interpretation of Quantitative Proteomics Results

, 14(3): 435 - 449

Teresa Nunez Villavicencio-Diaz, Arielis Rodriguez-Ulloa, Osmany Guirola-Cruz and Yasset Perez-Riverol


DOI: 10.2174/1568026613666131204105110




Alterations of the Kidney Cortex Proteome in Response to Exercise Training in Normoglycemic and Hyperglycemic Conditions

, 14(3): 450 - 461

Roger de Moraes, Richard H. Valente, Ileana R. Leon, Monique R.O. Trugilho, Antonio G. Pacheco, Antonio C.L. Nobrega, Marilia B. Gomes, Jonas Perales and Eduardo Tibirica


DOI: 10.2174/1568026613666131204115656




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