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Contents

Current Topics in Medicinal Chemistry, Volume 14 - Number 23


Metabolomics as a Tool for Drug Discovery and Personalised Medicine. A Review

, 14(23): 2627 - 2636

Annalaura Mastrangelo, Emily G Armitage, Antonia García and Coral Barbas


DOI: 10.2174/1568026614666141215124956



Phospholipid Bilayer Nanodiscs: A Powerful Tool to Study the Structural Organization and Biochemical Reactivity of Proteins in Membrane-like Environments

, 14(23): 2637 - 2646

Víctor M. Hernandez-Rocamora, Concepcion Garcia-Montanes and German Rivas


DOI: 10.2174/1568026614666141215142951



Membrane-Targeted Self-Assembling Cyclic Peptide Nanotubes

, 14(23): 2647 - 2661

Nuria Rodriguez-Vazquez, H. Lionel Ozores, Arcadio Guerra, Eva Gonzalez-Freire, Alberto Fuertes, Michele Panciera, Juan M. Priegue, Juan Outeiral, Javier Montenegro, Rebeca Garcia-Fandino, Manuel Amorin and Juan R. Granja


DOI: 10.2174/1568026614666141215143431




Modulation of Toll-Like Receptor 4. Insights from X-Ray Crystallography and Molecular Modeling

, 14(23): 2672 - 2683

Javier Klett, Jake Reeves, Nils Oberhauser, Lucia Perez-Regidor and Sonsoles Martin-Santamaria


DOI: 10.2174/1568026614666141215144831



Choline Kinase Active Site Provides Features for Designing Versatile Inhibitors

, 14(23): 2684 - 2693

L. Serran-Aguilera, R. Nuti, L.C. Lopez-Cara, P. Rios-Marco, M.P. Carrasco, C. Marco, A. Entrena, A. Macchiarulo and R. Hurtado-Guerrero


DOI: 10.2174/1568026614666141216093337



Chemoenzymatic Synthesis of Carbohydrates as Antidiabetic and Anticancer Drugs

, 14(23): 2694 - 2711

Andres R. Alcantara, Vittorio Pace, Pilar Hoyos, Manuel Sandoval, Wolfgang Holzer and Maria J. Hernaiz


DOI: 10.2174/1568026614666141215151056



Conformational Analysis of Peptides and Glycopeptides Derived from the Consensus Sequence for β-O-Glucosylation

, 14(23): 2712 - 2721

Victor J. Somovilla, Nuria Martinez-Saez, Alberto Fernandez-Tejada, Beatriz G. de la Torre, David Andreu, Jesus Jimenez-Barbero, Juan L. Asensio, Alberto Avenoza, Jesus H. Busto, Francisco Corzana and Jesus M. Peregrina


DOI: 10.2174/1568026614666141216100142



Synthesis and Biological Evaluation of 1,5-Naphthyridines as Topoisomerase I Inhibitors. A New Family of Antiproliferative Agents

, 14(23): 2722 - 2728

Concepcion Alonso, Maria Fuertes, Maria Gonzalez, Alicia Rodriguez-Gascon, Gloria Rubiales and Francisco Palacios


DOI: 10.2174/1568026614666141215152441




Triplet Excited States as a Source of Relevant (Bio)Chemical Information

, 14(23): 2734 - 2742

M. Consuelo Jimenez and Miguel A. Miranda


DOI: 10.2174/1568026614666141216100907



Poly(ε-caprolactone) Films with Favourable Properties for Neural Cell Growth

, 14(23): 2743 - 2749

N. Diban, J. Ramos-Vivas, S. Remuzgo-Martinez, I. Ortiz and A. Urtiaga


DOI: 10.2174/1568026614666141215153932




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