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Current Topics in Medicinal Chemistry

Volume 19, 32 Issues, 2019
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access

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    Chemistry, Medicinal

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Current Topics in Medicinal Chemistry, Volume 14 - Number 19

Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands

, 14(19): 2129 - 2142

Andrea Carotti, Maura Marinozzi, Chiara Custodi, Bruno Cerra, Roberto Pellicciari, Antimo Gioiello and Antonio Macchiarulo

DOI: 10.2174/1568026614666141112094058

Knocking on FXR's Door:The "Hammerhead"-Structure Series of FXRs Agonists - Amphiphilic Isoxazoles with Potent In Vitro and In Vivo Activities

, 14(19): 2143 - 2158

Christian Gege, Olaf Kinzel, Christoph Steeneck, Andreas Schulz and Claus Kremoser

DOI: 10.2174/1568026614666141112094430

Bile Acid Derivatives as Ligands of the Farnesoid X Receptor: Molecular Determinants for Bile Acid Binding and Receptor Modulation

, 14(19): 2159 - 2174

Antimo Gioiello, Bruno Cerra, Serena Mostarda, Chiara Guercini, Roberto Pellicciari and Antonio Macchiarulo

DOI: 10.2174/1568026614666141112100208

Recent Advances in Non-Steroidal FXR Antagonists Development for Therapeutic Applications

, 14(19): 2175 - 2187

Huang Huang, Yong Xu, Jin Zhu and Jian Li

DOI: 10.2174/1568026614666141112101840

Medicinal Chemistry and Pharmacological Effects of Farnesoid X Receptor (FXR) Antagonists

, 14(19): 2188 - 2205

Christina Lamers, Manfred Schubert-Zsilavecz and Daniel Merk

DOI: 10.2174/1568026614666141112103516

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