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Contents

Current Topics in Medicinal Chemistry, Volume 14 - Number 10


Recent Advances on the Enantioselective Synthesis of C-Nucleosides Inhibitors of Inosine Monophosphate Dehydrogenase (IMPDH)

, 14(10): 1212 - 1224

Pedro Merino, Mattia Ghirardello, Tomas Tejero, Ignacio Delso and Rosa Matute


DOI: 10.2174/1568026614666140423095331



Conformational Preferences of Chiral Acyclic Homooligomeric β2,2-Peptides

, 14(10): 1225 - 1234

Fernando Rodriguez, Francisco Corzana, Alberto Avenoza, Jesus Hector Busto, Jesus Manuel Peregrina and Maria del Mar Zurbano


DOI: 10.2174/1568026614666140423101226



Enantioselective Synthesis in Carbohydrate-Based Drug Discovery: Imino Sugars, Alkaloids and Macrolide Antibiotics

, 14(10): 1235 - 1243

Nuno M. Xavier and Amélia P. Rauter


DOI: 10.2174/1568026614666140423103848



Chiral Thiazoline and Thiazole Building Blocks for the Synthesis of Peptide- Derived Natural Products

, 14(10): 1244 - 1256

Xavier Just-Baringo, Fernando Albericio and Mercedes Alvarez


DOI: 10.2174/1568026614666140423105730



Enantiopure 1,2,3-Triazolyl-β-amino Acids via Click Cycloaddition Reaction on Racemic Alkynyl Precursors Followed by Separation of Stereoisomers

, 14(10): 1257 - 1270

Margarita Escudero-Casao, Alberto Vega-Penaloza and Eusebio Juaristi


DOI: 10.2174/1568026614666140423110420



Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes

, 14(10): 1271 - 1282

Carmen Nejera and Jose M. Sansano


DOI: 10.2174/1568026614666140423112145



Enantioselective Synthesis of PPAR (Peroxisome Proliferator-Activated Receptors) Agonists and Antagonists

, 14(10): 1283 - 1293

Pilar Goya, Ruth Perez-Fernandez, Rosario Gonzalez-Muniz and Jose Elguero


DOI: 10.2174/1568026614666140423112822



Recent Syntheses and Biological Activity of Lentiginosine and its Analogues

, 14(10): 1294 - 1307

Franca M. Cordero, Donatella Giomi and Alberto Brandi


DOI: 10.2174/1568026614666140423113226



Stereoselective Synthesis of Polysubstituted Piperazines and Oxopiperazines. Useful Building Blocks in Medicinal Chemistry

, 14(10): 1308 - 1316

Alessandro Mordini, Gianna Reginato, Massimo Calamante and Lorenzo Zani


DOI: 10.2174/1568026614666140423114013



Base Free Catalyzed Enantioselective Michael Reaction of bis(phenylsulfonyl)methane to α,β -Unsaturated Aldehydes under Iminium Activation

, 14(10): 1317 - 1322

Beatriz Alonso, Uxue Uria, Luisa Carrillo, Jose L. Vicario and Efraim Reyes


DOI: 10.2174/1568026614666140423114516




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