Contents

Current Topics in Medicinal Chemistry, Volume 14 - Number 1

Foreword:

, 14(1): 1

Allen B. Reitz


DOI: 10.2174/156802661401131226130252




Editorial (Thematic Issue: Nosocomial Infections: An Increasing Challenge to Medicinal Chemistry)

, 14(1): 2 - 3

Marcus Tullius Scotti, M. N. D. S. Cordeiro and Alejandro Speck-Planche


DOI: 10.2174/1568026613666131111101521




Structure Guided Design of Biotin Protein Ligase Inhibitors for Antibiotic Discovery

, 14(1): 4 - 20

Ashleigh S. Paparella, Tatiana P. Soares da Costa, Min Y. Yap, William Tieu, Matthew C. J. Wilce, Grant W. Booker, Andrew D. Abell and Steven W. Polyak


DOI: 10.2174/1568026613666131111103149




New Synthetic Antibiotics for the Treatment of Enterococcus and Campylobacter Infection

, 14(1): 21 - 39

Hai-Wei Xu, Shang-Shang Qin and Hong-Min Liu


DOI: 10.2174/1568026613666131113145544




Designing Type II Topoisomerase Inhibitors: A Molecular Modeling Approach

, 14(1): 40 - 50

Juan J. Perez, Cecylia S. Lupala and Patricia Gomez-Gutierrez


DOI: 10.2174/1568026613666131113150046




Structure-and-Mechanism-Based Design and Discovery of Type II Mycobacterium Tuberculosis Dehydroquinate Dehydratase Inhibitors

, 14(1): 51 - 63

Yuan Yao and Li Ze-Sheng


DOI: 10.2174/1568026613666131113150257




Docking and PLS Studies on a Set of Thiophenes RNA Polymerase Inhibitors Against Staphylococcus aureus

, 14(1): 64 - 80

Luciana Scotti, Edeltrudes de Oliveira Lima, Marcelo Sobral da Silva, Hamilton Ishiki, Igara de Oliveira Lima, Fillipe de Oliveira Pereira, Francisco Jaime Bezerra Mendonça Junior and Marcus Tullius Scotti


DOI: 10.2174/1568026613666131113151347




Next Generation Biofilm Inhibitors for Pseudomonas aeruginosa: Synthesis and Rational Design Approaches

, 14(1): 81 - 109

Mahesh S. Majik and Prakash T. Parvatkar


DOI: 10.2174/1568026613666131113152257




Filling the Pipeline - New Drugs for an Old Disease

, 14(1): 110 - 129

Matthias Stehr, Ayssar A. Elamin and Mahavir Singh


DOI: 10.2174/1568026613666131113152908




Prospects for Developing New Antibacterials Targeting Bacterial Type IIA Topoisomerases

, 14(1): 130 - 151

Tihomir Tomašić and Lucija Peterlin Mašič


DOI: 10.2174/1568026613666131113153251




Progress in the Discovery of Treatments for C. difficile Infection: A Clinical and Medicinal Chemistry Review

, 14(1): 152 - 175

Lissa S. Tsutsumi, Yaw B. Owusu, Julian G. Hurdle and Dianqing Sun


DOI: 10.2174/1568026613666131113154753




Computational Medicinal Chemistry for Rational Drug Design: Identification of Novel Chemical Structures with Potential Anti-Tuberculosis Activity

, 14(1): 176 - 188

Yuji Koseki and Shunsuke Aoki


DOI: 10.2174/1568026613666131113155042




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