Contents

Current Topics in Medicinal Chemistry, Volume 13 - Number 19

Editorial

Editorial (Thematic Issue: Recent Advances of Biology and Medicinal Chemistry of Prion Protein and Prions: On the Road to Therapeutics)

, 13(19): 2395 - 2396

Giuseppe Legname and Maria Laura Bolognesi


DOI: 10.2174/15680266113136660167




Strain Specificity and Drug Resistance in Anti-Prion Therapy

, 13(19): 2397 - 2406

Lakshmi Miller-Vedam and Sina Ghaemmaghami


DOI: 10.2174/15680266113136660168




NMR Structural Studies of Human Cellular Prion Proteins

, 13(19): 2407 - 2418

Ivana Biljan, Gregor Ilc, Gabriele Giachin, Giuseppe Legname and Janez Plavec


DOI: 10.2174/15680266113136660169




Computational Studies on the Prion Protein

, 13(19): 2419 - 2431

Giulia Rossetti, Salvatore Bongarzone and Paolo Carloni


DOI: 10.2174/15680266113136660170




Logical Design of Medical Chaperone for Prion Diseases

, 13(19): 2432 - 2440

Kazuo Kuwata


DOI: 10.2174/15680266113136660171




Prion Chemical Biology: On the Road to Therapeutics?

, 13(19): 2441 - 2464

Beining Chen, Mark Thompson, Jennifer Louth and Kai Guo


DOI: 10.2174/15680266113136660172




Therapy in Prion Diseases

, 13(19): 2465 - 2476

Gianluigi Forloni, Vladimiro Artuso, Ignazio Roiter, Michela Morbin and Fabrizio Tagliavini


DOI: 10.2174/15680266113136660173




Thienyl Pyrimidine Derivatives with PrPSc Oligomer-Inducing Activity are a Promising Tool to Study Prions

, 13(19): 2477 - 2483

Thibaut Imberdis, Adeline Ayrolles-Torro, Jean-Michel Verdier and Véronique Perrier


DOI: 10.2174/15680266113136660174




Hybrid Molecules Synergistically Acting Against Protein Aggregation Diseases

, 13(19): 2484 - 2490

Carsten Korth, Ralf Klingenstein and Andreas Müller-Schiffmann


DOI: 10.2174/15680266113136660175




Modulation of Prion by Small Molecules: From Monovalent to Bivalent and Multivalent Ligands

, 13(19): 2491 - 2503

Matteo Staderini, Giuseppe Legname, Maria Laura Bolognesi and J. Carlos Menéndez


DOI: 10.2174/15680266113136660176




Animal Models for Testing Anti-Prion Drugs

, 13(19): 2504 - 2521

Natalia Fernández-Borges, Saioa R. Elezgarai, Hasier Eraña and Joaquín Castilla


DOI: 10.2174/15680266113136660177




Amyloid-Binding Compounds and their Anti-Prion Potency

, 13(19): 2522 - 2532

Kenta Teruya and Katsumi Doh-ura


DOI: 10.2174/15680266113136660178




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