Contents

Current Topics in Medicinal Chemistry, Volume 12 - Number 7

Editorial [Hot Topic: TB Drug Development (Guest Editor: Courtney C. Aldrich)]

, 12(7): 671

Courtney C. Aldrich


DOI: 10.2174/156802612799984553




Targeting InhA, the FASII Enoyl-ACP Reductase: SAR Studies on Novel Inhibitor Scaffolds

, 12(7): 672 - 693

Pan Pan and Peter J. Tonge


DOI: 10.2174/156802612799984535




Drug Design and Identification of Potent Leads Against Mycobacterium tuberculosis Thymidine Monophosphate Kinase

, 12(7): 694 - 705

S. Van Calenbergh, S. Pochet and H. Munier-Lehmann


DOI: 10.2174/156802612799984580




Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (Dxr): A Review of the Synthesis and Biological Evaluation of Recent Inhibitors

, 12(7): 706 - 728

Emily R. Jackson and Cynthia S. Dowd


DOI: 10.2174/156802612799984599




Derivatives of 3-Isoxazolecarboxylic Acid Esters - A Potent and Selective Compound Class against Replicating and Nonreplicating Mycobacterium tuberculosis

, 12(7): 729 - 734

Annamaria Lilienkampf, Marco Pieroni, Scott G. Franzblau, William R. Bishai and Alan P. Kozikowski


DOI: 10.2174/156802612799984544




Natural Products as Leads for Tuberculosis Drug Development

, 12(7): 735 - 765

Christine E. Salomon and Lori E. Schmidt


DOI: 10.2174/156802612799984526




Adenylating Enzymes in Mycobacterium tuberculosis as Drug Targets

, 12(7): 766 - 796

Benjamin P. Duckworth, Kathryn M. Nelson and Courtney C. Aldrich


DOI: 10.2174/156802612799984571




Obituary

, 12(7): 797

Emilio Jirillo


DOI: 10.2174/156802612799984562




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