Contents

Current Topics in Medicinal Chemistry, Volume 12 - Number 6

Editorial [Hot Topic :Current Advances In Therapeutic Applications of Nuclear Receptors (Guest Editor: Stefano Fiorucci)]

, 12(6): 484 - 485

Stefano Fiorucci


DOI: 10.2174/156802612799436696




General Molecular Biology and Architecture of Nuclear Receptors

, 12(6): 486 - 504

Michal Pawlak, Philippe Lefebvre and Bart Staels


DOI: 10.2174/156802612799436641




Retinoid Receptors and Therapeutic Applications of RAR/RXR Modulators

, 12(6): 505 - 527

Albane le Maire, Susana Alvarez, Pattabhiraman Shankaranarayanan, Angel R de Lera, William Bourguet and Hinrich Gronemeyer


DOI: 10.2174/156802612799436687




Current Status of Vitamin D Signaling and Its Therapeutic Applications

, 12(6): 528 - 547

Carsten Carlberg and Ferdinand Molnar


DOI: 10.2174/156802612799436623




Biology and Therapeutic Applications of Peroxisome Proliferator- Activated Receptors

, 12(6): 548 - 584

Maria P. Menendez-Gutierrez, Tamas Roszer and Mercedes Ricote


DOI: 10.2174/156802612799436669




Update on Cardiovascular Safety of PPARgamma Agonists and Relevance to Medicinal Chemistry and Clinical Pharmacology

, 12(6): 585 - 604

Andreea Ciudin, Cristina Hernandez and Rafael Simo


DOI: 10.2174/156802612799436632




Development of FXR, PXR and CAR Agonists and Antagonists for Treatment of Liver Disorders

, 12(6): 605 - 624

Stefano Fiorucci, Angela Zampella and Eleonora Distrutti


DOI: 10.2174/156802612799436678




Molecular Determinants of Gastrointestinal and Liver Cancers: Role of Bile Acid Activated Nuclear Receptors

, 12(6): 625 - 636

Barbara Renga, Andrea Mencarelli, Sabrina Cipriani and Eleonora Distrutti


DOI: 10.2174/156802612799436614




Natural Ligands for Nuclear Receptors: Biology and Potential Therapeutic Applications

, 12(6): 637 - 669

Maria Valeria D'Auria, Valentina Sepe and Angela Zampella


DOI: 10.2174/156802612799436650




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