Contents

Current Topics in Medicinal Chemistry, Volume 12 - Number 4

Editorial [Hot Topic:The Indolylglyoxylamide Scaffold as an Useful Tool to Obtain Anxiolytic Agents (Guest Editors: Sabrina Taliani & Federico Da Settimo )]

, 12(4): 236 - 237

Sabrina Taliani and Federico Da Settimo


DOI: 10.2174/156802612799078801




Treatment Strategies of Obsessive-Compulsive Disorder and Panic Disorder/Agoraphobia

, 12(4): 238 - 253

Donatella Marazziti, Marina Carlini and Liliana Dell'Osso


DOI: 10.2174/1568026799078688




The GABAA-BZR Complex as Target for the Development of Anxiolytic Drugs

, 12(4): 254 - 269

Maria Letizia Trincavelli, Eleonora Da Pozzo, Simona Daniele and Claudia Martini


DOI: 10.2174/1568026799078787




Translocator Protein as a Promising Target for Novel Anxiolytics

, 12(4): 270 - 285

Barbara Costa, Eleonora Da Pozzo and Claudia Martini


DOI: 10.2174/156802612799078720




Medicinal Chemistry of Indolylglyoxylamide GABAA/BzR High Affinity Ligands: Identification of Novel Anxiolytic/Non Sedative Agents

, 12(4): 286 - 311

Silvia Salerno, Federico Da Settimo, Sabrina Taliani, Francesca Simorini, Concettina La Motta, Giacomo Fornaciari and Anna Maria Marini


DOI: 10.2174/156802612799078847




Geometrically Constrained Derivatives of Indolylglyoxylamides as Ligands Binding the GABAA/BzR Complex

, 12(4): 312 - 320

S. Sartini, M. Morelli, F. Simorini, S. Taliani, S. Salerno, A. M. Marini, F. Da Settimo and C. La Motta


DOI: 10.2174/156802612799078829




From the Pharmacophore to the Homology Model of the Benzodiazepine Receptor: The Indolyglyoxylamides Affair

, 12(4): 321 - 332

Barbara Cosimelli, Sandro Cosconati, Luciana Marinelli, Ettore Novellino and Giovanni Greco


DOI: 10.2174/156802612799078702




Medicinal Chemistry of Indolylglyoxylamide TSPO High Affinity Ligands with Anxiolytic-Like Effects

, 12(4): 333 - 351

Francesca Simorini, Anna Maria Marini, Sabrina Taliani, Concettina La Motta, Silvia Salerno, Isabella Pugliesi and Federico Da Settimo


DOI: 10.2174/156802612799078766




Computational Studies on Translocator Protein (TSPO) and its Ligands

, 12(4): 352 - 359

Gabriella Ortore, Tiziano Tuccinardi and Adriano Martinelli


DOI: 10.2174/156802612799078667




Recent Developments in Potential Anxiolytic Agents Targeting GABAA/BzR Complex or the Translocator Protein (18kDa) (TSPO)

, 12(4): 360 - 370

Caroline Nothdurfter, Rainer Rupprecht and Gerhard Rammes


DOI: 10.2174/156802612799078748




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