Contents

Current Topics in Medicinal Chemistry, Volume 12 - Number 20

Editorial (Hot Topic: Monoamine Oxidase as a Target in Medicinal Chemistry and Drug Discovery)

, 12(20): 2115

Dolores Vina and Maria Joao Matos


DOI: 10.2174/1568026611212200001




Parkinson's Disease Management. Part II- Discovery of MAO-B Inhibitors Based on Nitrogen Heterocycles and Analogues

, 12(20): 2116 - 2130

Joana Reis, Igor Encarnacao, Alexandra Gaspar, Aliuska Morales, Nuno Milhazes and Fernanda Borges


DOI: 10.2174/1568026611212200002




Herbal Natural Products As a Source of Monoamine Oxidase Inhibitors: A Review

, 12(20): 2131 - 2144

Dolores Vina, Silvia Serra, Manuel Lamela and Giovanna Delogu


DOI: 10.2174/1568026611212200003




Monoamine Oxidase Inhibitors: Ten Years of Docking Studies

, 12(20): 2145 - 2162

Giulio Ferino, Santiago Vilar, Maria J. Matos, Eugenio Uriarte and Enzo Cadoni


DOI: 10.2174/1568026611212200004




Recent Developments in the Regulation of Monoamine Oxidase Form and Function: Is the Current Model Restricting Our Understanding of the Breadth of Contribution of Monoamine Oxidase to Brain [dys]Function?

, 12(20): 2163 - 2176

Darrell D. Mousseau and Glen B. Baker


DOI: 10.2174/1568026611212200005




Type A and B Monoamine Oxidase in Age-Related Neurodegenerative Disorders: Their Distinct Roles in Neuronal Death and Survival

, 12(20): 2177 - 2188

Makoto Naoi, Wakako Maruyama and Keiko Inaba-Hasegawa


DOI: 10.2174/1568026611212200006




Monoamine Oxidases: The Biochemistry of the Proteins As Targets in Medicinal Chemistry and Drug Discovery

, 12(20): 2189 - 2209

Rona R. Ramsay


DOI: 10.2174/1568026611212200007




Focusing on New Monoamine Oxidase Inhibitors: Differently Substituted Coumarins As An Interesting Scaffold

, 12(20): 2210 - 2239

Maria Joao Matos, Dolores Vina, Saleta Vazquez-Rodriguez, Eugenio Uriarte and Lourdes Santana


DOI: 10.2174/1568026611212200008




Discovery and Optimization of Pyrazoline Derivatives As Promising Monoamine Oxidase Inhibitors

, 12(20): 2240 - 2257

Daniela Secci, Simone Carradori, Adriana Bolasco, Bruna Bizzarri, Melissa D’Ascenzio and Elias Maccioni


DOI: 10.2174/1568026611212200009




Predicting Monoamine Oxidase Inhibitory Activity Through Ligand-Based Models

, 12(20): 2258 - 2274

Santiago Vilar, Giulio Ferino, Elias Quezada, Lourdes Santana and Carol Friedman


DOI: 10.2174/1568026611212200010




History and Therapeutic Use of MAO-A Inhibitors: A Historical Perspective of MAO-A Inhibitors As Antidepressant Drug

, 12(20): 2275 - 2282

Matilde Yanez, Juan Fernando Padin, Juan Alberto Arranz-Tagarro, Mercedes Camina and Reyes Laguna


DOI: 10.2174/1568026611212200011




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