Contents

Current Topics in Medicinal Chemistry, Volume 12 - Number 19

Editorial

Editorial (Hot Topic: Synthetic, Natural and Related Compounds: New Approach to Chronic Diseases Studies)

, 12(19): 2035 - 2036

Fátima Regina Mena Barreto Silva and Luisa Helena Cazarolli


DOI: 10.2174/1568026611212190001




Docking, Synthesis and Anti-Diabetic Activity of Novel Sulfonylhydrazone Derivatives Designed as PPAR-Gamma Agonists

, 12(19): 2037 - 2048

Gisele Zapata-Sudo, Lidia M. Lima, Sharlene L. Pereira, Margarete M. Trachez, Filipe P. da Costa, Beatriz J. Souza, Carlos E. S. Monteiro, Nelilma C. Romeiro, Everton D. D’Andrea, Roberto T. Sudo and Eliezer J. Barreiro


DOI: 10.2174/1568026611212190002




Acylhydrazones Contribute to Serum Glucose Homeostasis Through Dual Physiological Targets

, 12(19): 2049 - 2058

Marisa Jadna Silva Frederico, Allisson Jhonatan Gomes Castro, Alessandra Mascarello, Camila Pires Mendes, Virginia Dermachi Kappel, Taisa Regina Stumpf, Paulo Cesar Leal, Ricardo Jose Nunes, Rosendo Augusto Yunes and Fatima Regina Mena Barreto Silva


DOI: 10.2174/1568026611212190003




Estrogen Receptor 1 Agonist PPT Stimulates Slc2a4 Gene Expression and Improves Insulin-Induced Glucose Uptake in Adipocytes

, 12(19): 2059 - 2069

R. S. Campello, A. B. Alves-Wagner, T. F. Lucas, R. C. Mori, D. T. Furuya, C. S. Porto and U. F. Machado


DOI: 10.2174/1568026611212190004




The Central Nervous System as a Promising Target to Treat Diabetes Mellitus

, 12(19): 2070 - 2081

Jose Donato Jr.


DOI: 10.2174/1568026611212190005




Equinatoxin II Potentiates Temozolomide- and Etoposide-Induced Glioblastoma Cell Death

, 12(19): 2082 - 2093

Suzana Assad Kahn, Deborah Biasoli, Celina Garcia, Luiz Henrique M. Geraldo, Bruno Pontes, Morgana Sobrinho, Ana Carina Bon Frauches, Luciana Romao, Rossana C. Soletti, Fernando dos Santos Assuncao, Fernanda Tovar-Moll, Jorge Marcondes de Souza, Flavia R.S. Lima, Gregor Anderluh and Vivaldo Moura-Neto


DOI: 10.2174/1568026611212190006




Biological Evaluation of 3-Acyl-2-Arylamino-1,4-Naphthoquinones as Inhibitors of Hsp90 Chaperoning Function

, 12(19): 2094 - 2102

David Rios, Julio Benites, Jaime A. Valderrama, Mirelle Farias, Rozangela C. Pedrosa, Julien Verrax and Pedro Buc Calderon


DOI: 10.2174/1568026611212190007




Effects of Natural Compounds on Xenopus Embryogenesis: A Potential Read Out for Functional Drug Discovery Targeting Wnt/β-catenin Signaling

, 12(19): 2103 - 2113

Nathalia G. Amado, Barbara F. Fonseca, Debora Malta Cerqueira, Alice H. Reis, Alessandro Bolis Costa Simas, Ricardo Machado Kuster, Fabio A. Mendes and Jose G. Abreu


DOI: 10.2174/1568026611212190008




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