Contents

Current Topics in Medicinal Chemistry, Volume 12 - Number 11

Editorial [Hot Topic: Pharmaceutical R&D: A Knowledge-Intensive Multidisciplinary Approach (Guest Editor: Gary W. Caldwell)]

, 12(11): 1223

Gary W. Caldwell


DOI: 10.2174/156802612800672899




Recent Advances in Positron Emission Tomography (PET) Radiotracers for Imaging Phosphodiesterases

, 12(11): 1224 - 1236

Jose Ignacio Andres, Meri De Angelis, Jesus Alcazar, Sofie Celen and Guy Bormans


DOI: 10.2174/156802612800672853




An Integrated Data Management Framework for Drug Discovery – From Data Capturing to Decision Support

, 12(11): 1237 - 1242

Walter Cedeno, Simson Alex, Edward P. Jaeger, Dimitris K. Agrafiotis and Victor S. Lobanov


DOI: 10.2174/156802612800672862




A Novel Method for Determination of Drug Distribution in Rat Brain Tissue Sections by LC/MS/MS: Functional Tissue Microanalysis

, 12(11): 1243 - 1249

John A. Masucci, Andrew D. Mahan, Joseph D. Kwasnoski and Gary W. Caldwell


DOI: 10.2174/156802612800672916




Screening Strategy for Chiral and Achiral Separations in Supercritical Fluid Chromatography Mode

, 12(11): 1250 - 1263

David Speybrouck, David Corens and Jean-Michel Argoullon


DOI: 10.2174/156802612800672907




Chromatographic Separation of Bioactive Oxycholesterols by GC, HPLC and SFC

, 12(11): 1264 - 1270

Heather McAllister and Jiejun Wu


DOI: 10.2174/156802612800672880




Insights from Structural Analysis of cFMS/Inhibitor Complexes: Common Interactions Via Three Structurally Dissimilar Scaffolds

, 12(11): 1271 - 1281

Renee L. DesJarlais


DOI: 10.2174/156802612800672835




The IC50 Concept Revisited

, 12(11): 1282 - 1290

Gary W. Caldwell, Zhengyin Yan, Wensheng Lang and John A. Masucci


DOI: 10.2174/156802612800672844




The Current Status of Time Dependent CYP Inhibition Assay and In Silico Drug-drug Interaction Predictions

, 12(11): 1291 - 1297

Zhengyin Yan and Gary W. Caldwell


DOI: 10.2174/156802612800672871




Small Molecule Compound Logistics Outsourcing – Going Beyond the “Thought Experiment”

, 12(11): 1298 - 1308

Devon L. Ramsay, Joseph D. Kwasnoski and Gary W. Caldwell


DOI: 10.2174/156802612800672826




Webmaster Contact: info@benthamscience.org
Copyright © 2018 Bentham Science