Contents

Current Topics in Medicinal Chemistry, Volume 11 - Number 7

Editorial [Hot topic: Effect of Stereochemistry in Medicinal Chemistry and Drug Discovery (Guest Editor: Simona Rapposelli)]

, 11(7): 758 - 759

Simona Rapposelli


DOI: 10.2174/156802611795165179




The Significance of Chirality in Drug Design and Development

, 11(7): 760 - 770

W. H. Brooks, W. C. Guida and K. G. Daniel


DOI: 10.2174/156802611795165098




Numerical Descriptors for the Characterization of Chiral Compounds and their Applications in Modeling Biological and Toxicological Activities

, 11(7): 771 - 787

Ramanathan Natarajan and Subhash C. Basak


DOI: 10.2174/156802611795165197




Selectivity Filters to Edit Out Deleterious Side Effects in Kinase Inhibitors

, 11(7): 788 - 799

Sean Sessel and Ariel Fernandez


DOI: 10.2174/156802611795165089




Chiral Kinase Inhibitors

, 11(7): 800 - 809

Jian-kang Jiang, Min Shen, Craig J. Thomas and Mathew B. Boxer


DOI: 10.2174/156802611795165052




Stereochemistry at the Forefront in the Design and Discovery of Novel Anti-tuberculosis Agents

, 11(7): 810 - 818

Qingqing Huang, Rong He and Alan P. Kozikowski


DOI: 10.2174/156802611795165205




Structural Insight Into the Crucial Role of Ligand Chirality in the Activation of PPARs by Crystallographic Methods

, 11(7): 819 - 839

F. Loiodice and G. Pochetti


DOI: 10.2174/156802611795165106




The Importance of Stereochemistry on the Actions of Vitamin D

, 11(7): 840 - 859

G. Chiellini and H. F. DeLuca


DOI: 10.2174/156802611795165016




Structural Requirements to Obtain Highly Potent and Selective 18 kDa Translocator Protein (TSPO) Ligands

, 11(7): 860 - 886

Sabrina Taliani, Isabella Pugliesi and Federico Da Settimo


DOI: 10.2174/156802611795165142




Glutamate Receptor Agonists: Stereochemical Aspects

, 11(7): 887 - 906

Stine Byskov Vogensen, Jeremy R. Greenwood, Lennart Bunch and Rasmus Praetorius Clausen


DOI: 10.2174/156802611795164990




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