Contents

Current Topics in Medicinal Chemistry, Volume 11 - Number 23

Editorial [Hot Topic: The Medicinal Chemistry of Ubiquitin-Proteasome Pathway (UPP) and Its Relevance in Drug Discovery (Guest Editor: Yongqiang Zhu)]

, 11(23): 2849

Yongqiang Zhu


DOI: 10.2174/156802611798281339




Proteasome Structure, Function, and Lessons Learned from Beta-Lactone Inhibitors

, 11(23): 2850 - 2878

Michael Groll and Barbara C. Potts


DOI: 10.2174/156802611798281320




Ubiquitination in Rho Signaling

, 11(23): 2879 - 2887

Feng Ding, Zhenyu Yin and Hong-Rui Wang


DOI: 10.2174/156802611798281357




Targeting the Ubiquitin-Proteasome Pathway: An Emerging Concept in Cancer Therapy

, 11(23): 2888 - 2905

Michael Frezza, Sara Schmitt and Q. Ping Dou


DOI: 10.2174/156802611798281311




Synthesis of Salinosporamide A and Its Analogs as 20S Proteasome Inhibitors and SAR Summarization

, 11(23): 2906 - 2922

Yuheng Ma, Lili Qu, Zhenming Liu, Liangren Zhang, Zhenjun Yang and Lihe Zhang


DOI: 10.2174/156802611798281302




The Immunoproteasome: An Emerging Therapeutic Target

, 11(23): 2923 - 2930

Wooin Lee and Kyung Bo Kim


DOI: 10.2174/156802611798281348




Progress of Computer-Aided Drug Design (CADD) of Proteasome Inhibitors

, 11(23): 2931 - 2944

Meng Lei, Yunde Liu, Yongqiang Zhu and Zhenming Liu


DOI: 10.2174/156802611798281366




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