Contents

Current Topics in Medicinal Chemistry, Volume 11 - Number 22

Editorial [Hot Topic: The Medicinal Chemistry of Hybrid-Based Drugs Targeting Multiple Sites of Action (Guest Editors: Jose Marco-Contelles, & Elena Soriano)]

, 11(22): 2714 - 2715

J. Marco-Contelles and E. Soriano


DOI: 10.2174/156802611798184382




Hybrid-Based Multi-Target Ligands for the Treatment of Alzheimer's Disease

, 11(22): 2716 - 2730

Angela Rampa, Federica Belluti, Silvia Gobbi and Alessandra Bisi


DOI: 10.2174/156802611798184409




A Hydrazide Linker Strategy for Heterobivalent Compounds as Ortho- and Allosteric Ligands of Acetylcholine-Binding Proteins

, 11(22): 2731 - 2748

Paul W. Elsinghorst, Wolfgang Hartig, Daniela Gundisch, Klaus Mohr, Christian Trankle and Michael Gutschow


DOI: 10.2174/156802611798184427




Epigenetic Multiple Modulators

, 11(22): 2749 - 2787

Rosana Alvarez, Lucia Altucci, Hinrich Gronemeyer and Angel R. de Lera


DOI: 10.2174/156802611798184436




Lights and Shadows on Monoamine Oxidase Inhibition in Neuroprotective Pharmacological Therapies

, 11(22): 2788 - 2796

Claudia Binda, Erika M. Milczek, Daniele Bonivento, Jin Wang, Andrea Mattevi and Dale E. Edmondson


DOI: 10.2174/156802611798184355




Multitarget-Directed Ligands: Innovative Chemical Probes and Therapeutic Tools Against Alzheimer's Disease

, 11(22): 2797 - 2806

Maria Laura Bolognesi, Elena Simoni, Michela Rosini, Anna Minarini, Vincenzo Tumiatti and Carlo Melchiorre


DOI: 10.2174/156802611798184373




1,8-Naphthyridine derivatives as Cholinesterases Inhibitors and Cell Ca2+ Regulators, a Multitarget Strategy for Alzheimer's Disease

, 11(22): 2807 - 2823

Javier Egea and Cristobal de los Rios


DOI: 10.2174/156802611798184418




Multi-Target-Directed Ligands as Innovative Tools to Combat Trypanosomatid Diseases

, 11(22): 2824 - 2833

Maria Laura Bolognesi


DOI: 10.2174/156802611798184391




Multitarget Antithrombotic Drugs

, 11(22): 2834 - 2848

Milos Ilic, Danijel Kikelj and Janez Ilas


DOI: 10.2174/156802611798184364




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