Contents

Current Topics in Medicinal Chemistry, Volume 10 - Number 17

Editorial [Hot topic: Imaging of ABC Transporter Function and Expression (Guest Editors: Nicola Antonio Colabufo and Aren van Waarde)]

, 10(17): 1701 - 1702

Nicola Antonio Colabufo and Aren van Waarde


DOI: 10.2174/156802610792928068




Substrates, Inhibitors and Activators of P-glycoprotein: Candidates for Radiolabeling and Imaging Perspectives

, 10(17): 1703 - 1714

Nicola A. Colabufo, Francesco Berardi, Maria Grazia Perrone, Elena Capparelli, Mariangela Cantore, Carmela Inglese and Roberto Perrone


DOI: 10.2174/156802610792928022




N,N-bis(Cyclohexanol)amine Aryl Esters: The Discovery of a New Class of Highly Potent Inhibitors of Transporter-Dependent Multidrug Resistance (MDR)

, 10(17): 1715 - 1731

E. Teodori, S. Dei, C. Martelli and S. Scapecchi


DOI: 10.2174/156802610792928031




Modulators of Multidrug Resistance Proteins in the Management of Anticancer and Antimicrobial Drug Resistance and the Treatment of Inflammatory Diseases

, 10(17): 1732 - 1756

An-Kui Yang, Zhi-Wei Zhou, Min-Qian Wei, Jun-Ping Liu and Shu-Feng Zhou


DOI: 10.2174/156802610792928040




Reversal of Multidrug Resistance by Natural Substances from Plants

, 10(17): 1757 - 1768

Q. Wang, K. Michalak, O. Wesolowska, J. Deli, P. Molnar, J. Hohmann, J. Molnar and H. Engi


DOI: 10.2174/156802610792928103




Using Structural and Mechanistic Information to Design Novel Inhibitors/Substrates of P-Glycoprotein

, 10(17): 1769 - 1774

Freya Klepsch, Thomas Stockner, Thomas Erker, Markus Muller, Peter Chiba and Gerhard F. Ecker


DOI: 10.2174/156802610792928004




11C-verapamil to Assess P-gp Function in Human Brain During Aging,Depression and Neurodegenerative Disease

, 10(17): 1775 - 1784

A. L. Bartels, O. L. de Klerk, R. Kortekaas, J. J. de Vries and K. L. Leenders


DOI: 10.2174/156802610792928059




Imaging of P-glycoprotein Function and Expression to Elucidate Mechanisms of Pharmacoresistance in Epilepsy

, 10(17): 1785 - 1791

Wolfgang Loscher and Oliver Langer


DOI: 10.2174/156802610792928095




PET Imaging of Multidrug Resistance in Tumors Using 18F-Fluoropaclitaxel

, 10(17): 1792 - 1798

Karen A. Kurdziel and Dale O. Kiesewetter


DOI: 10.2174/156802610792928077




Using PET Studies of P-gp Function to Elucidate Mechanisms Underlying the Disposition of Drugs

, 10(17): 1799 - 1809

Stina Syvanen and Margareta Hammarlund-Udenaes


DOI: 10.2174/156802610792927997




PET Imaging of MRP1 Function in the Living Brain: Method Development and Future Perspectives

, 10(17): 1810 - 1819

T. Okamura, T. Kikuchi and T. Irie


DOI: 10.2174/156802610792927988




Carbon-11 Labeled Tracers for In Vivo Imaging of P-Glycoprotein Function: Kinetics, Advantages and Disadvantages

, 10(17): 1820 - 1833

Gert Luurtsema, Joost Verbeek, Mark Lubberink, Adriaan A. Lammertsma, Rudi Dierckx, Philip Elsinga, Albert D. Windhorst and Aren van Waarde


DOI: 10.2174/156802610792928013




Probing Multidrug Resistance P-glycoprotein Transporter Activity with SPECT Radiopharmaceuticals

, 10(17): 1834 - 1845

David Piwnica-Worms and Vijay Sharma


DOI: 10.2174/156802610792928086




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