Contents

Current Topics in Medicinal Chemistry, Volume 1 - Number 5

Preface

, 1(5): i

G. W. Caldwell


DOI: 10.2174/1568026013394903




The New Pre-Preclinical Paradigm: Compound Optimization in Early and Late Phase Drug Discovery

, 1(5): 353 - 366

Gary W. Caldwell, David M. Ritchie, John A. Masucci, William Hageman and Zhengyin Yan


DOI: 10.2174/1568026013394949




Strategies for Absorption Screening in Drug Discovery and Development

, 1(5): 367 - 383

Hilde Bohets, Pieter Annaert, Geert Mannens, Ludy van Beijsterveldt, Katelijne Anciaux, Peter Verboven, Willem Meuldermans and Karel Lavrijsen


DOI: 10.2174/1568026013394886




Assessing the Absorption of New Pharmaceuticals

, 1(5): 385 - 401

Ismael J. Hidalgo


DOI: 10.2174/1568026013395010




Metabolism Profiling, and Cytochrome P450 Inhibition & Induction in Drug Discovery

, 1(5): 403 - 425

Zhengyin Yan and Gary W. Caldwell


DOI: 10.2174/1568026013395001




Nuclear Magnetic Resonance as a Tool in Drug Discovery, Metabolism and Disposition

, 1(5): 427 - 441

Susan Sondej Pochapsky and Thomas C. Pochapsky


DOI: 10.2174/1568026013394967




Tailoring Bioanalysis for PK Studies Supporting Drug Discovery

, 1(5): 443 - 461

P.M.M.B.L. Timmerman, R. de Vries and B.A. Ingelse


DOI: 10.2174/1568026013394921




The Use of On-line and Off-line Chromatographic Extraction Techniques coupled with Mass Spectrometry for Support of In Vivo and In Vitro Assays in Drug Discovery

, 1(5): 463 - 471

John A. Masucci, Gary W. Caldwell, William J. Jones, Stephen J. Juzwin, Patrick J. Sasso and Mary Evangelisto


DOI: 10.2174/1568026013394985




Webmaster Contact: info@benthamscience.org
Copyright © 2018 Bentham Science