Contents

Current Topics in Medicinal Chemistry, Volume 1 - Number 2

Foreword

, 1(2): i

Rick Ewing and Henry Pauls


DOI: 10.2174/1568026013395443




The Design of Competitive, Small-molecule Inhibitors of Coagulation Factor Xa

, 1(2): 83 - 100

Henry W. Pauls and William R. Ewing


DOI: 10.2174/1568026013395515




Discovery of Transition State Factor Xa Inhibitors as Potential Anticoagulant Agents

, 1(2): 101 - 119

Bing-Yan Zhu, Wenrong Huang, Ting Su, Charles Marlowe, Uma Sinha, Stan Hollenbach and Robert M. Scarborough


DOI: 10.2174/1568026013395425




Discovery of the Factor Xa Inhibitor, ZK 807834 (CI-1031)

, 1(2): 121 - 136

David R. Light and William J. Guilford


DOI: 10.2174/1568026013395498




The Design and Synthesis of Noncovalent Factor Xa Inhibitors

, 1(2): 137 - 149

M. L. Quan and R. R. Wexler


DOI: 10.2174/1568026013395407




Coagulation Factor Xa Inhibition: Biological Background and Rationale

, 1(2): 151 - 159

Robert J. Leadley and Jr.


DOI: 10.2174/1568026013395380




The Use of 3D Structural Data in the Design of Specific Factor Xa Inhibitors

, 1(2): 161 - 174

Sebastien Maignan and Vincent Mikol


DOI: 10.2174/1568026013395461




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