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Current Topics in Medicinal Chemistry

Volume 19, 32 Issues, 2019
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access

Ranking and Category

  • 20th of 61 in

    Chemistry, Medicinal

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Articles Ahead of Print






Chemical Intuition in Drug Design and Discovery


Julia Galvez B. Pedreira, Lucas S. Franco and Eliezer J. Barreiro*


DOI: 10.2174/1568026619666190620144142
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Antitumoral Potential of Lansbermin-I, a Novel Disintegrin from Porthidium lansbergii lansbergii Venom on Breast Cancer Cells


Leonel Montealegre-Sánchez*, Sarah N. C. Gimenes, Daiana S. Lopes, Samuel C. Teixeira, Luis Solano-Redondo, Veridiana de M. Rodrigues and Eliécer Jiménez-Charris*


DOI: 10.2174/1568026619666190806151401
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Bothrops alternatus Snake Venom Induces Cytokine Expression and Oxidative Stress on Renal Function


Francisco Assis Nogueira Júnior, Antonio Rafael Coelho Jorge, Aline Diogo Marinho, João Alison de Moraes Silveira, Natacha Teresa Queiroz Alves, Pedro Henrique Sá Costa, Paula Letícia Braga e Silva, Adriano José Maia Chaves-Filho, Dânya Bandeira Lima, Tiago Lima Sampaio, Glayciane Bezerra de Morais, Janaina Serra Azul Monteiro Evangelista, Alice Maria Costa Martins, Rui Seabra Ferreira Jr., Danielle Silveira Macedo, Roberta Jeane Bezerra Jorge* and Helena Serra Azul Monteiro


DOI: 10.2174/1568026619666190809100319
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Renal Alterations Induced by the Venom of Colombian Scorpion Centruroides Margaritatus


Jessica Dayana Galíndez-Cerón, Roberta Jeane Bezerra Jorge*, Mario H. Chavez-Acosta, Antonio Rafael Coelho Jorge, Natacha Teresa Queiroz Alves, Mara de Moura Gondim Prata, Francisco Adelvane de Paulo Rodrigues, Alexandre Havt, Tiago Lima Sampaio, Alice Maria Costa Martins, Jimmy Alexander Guerrero-Vargas, Helena Serra Azul Monteiro and José T. Beltrán Vidal


DOI: 10.2174/1568026619666190731143523
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Venoms and Isolated Toxins from Snakes of Medical Impact in the Northeast Argentina: State of the Art. Potential Pharmacological Applications


María Emilia Garcia Denegri, Soledad Bustillo, Claudia Carolina Gay, Andrea Van De Velde, Gabriela Gomez, Silvina Echeverría, María Del Carmen Gauna Pereira, Silvana Maruñak, Sandra Nuñez, Fabián Bogado, Matías Sanchez, Gladys Pamela Teibler, Luciano Fusco* and Laura Cristina Ana Leiva*


DOI: 10.2174/1568026619666190725094851
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Isolation, Biochemical Characterization and Antiparasitic Activity of BmatTX-IV, A Basic Lys49-Phospholipase A2 from the Venom of Bothrops mattogrossensis from Paraguay


Jorge Javier Alfonso, Anderson M. Kayanoa, Ana Fidelina Gómez Garay, Rodrigo Simões-Silva, Juliana C. Sobrinho, Santiago Vourliotis, Andreimar M. Soares, Leonardo A. Calderon and Maria Celeste Vega Gómez*


DOI: 10.2174/1568026619666190723154756
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Plants and Phytocompounds Active Against Bothrops Venoms


Roberta Jeane Bezerra Jorge, René Duarte Martins, Renata Mendonça Araújo, Meykson Alexandre da Silva, Helena Serra Azul Monteiro and Rafael Matos Ximenes*


DOI: 10.2174/1568026619666190723153925
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Utilization of the Plant Clusia Fluminensis Planch & Triana Against Some Toxic Activities of the Venom of Bothrops jararaca and B. jararacussu Snake Venom Toxic Activities


Aldo Rodrigues da Silva, Maria Carolina Anholeti, Marcia Pietroluongo, Eladio Flores Sanchez, Alessandra Leda Valverde, Selma Ribeiro de Paiva, Maria Raquel Figueiredo, Maria Auxiliadora Coelho Kaplan and André Lopes Fuly*


DOI: 10.2174/1568026619666190724160711
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Antimyotoxic Activity of Synthetic Peptides Derived from Bothrops atrox Snake Gamma Phospholipase A2 Inhibitor Selected by Virtual Screening


J.C. Sobrinho, A.F. Francisco, R. Simões-Silva, A.M. Kayano, J.J. Alfonso, A.F. Gomez, A. Arruda, A.S. Ferreira, A.P.A. Santos, M.B. Luiz, C. B. G. Teles, S. S. Pereira, F.B. Zanchi, L.A. Calderon, J.P. Zuliani and A.M. Soares*


DOI: 10.2174/1568026619666190725102812
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The Anthelmintic Effect on Strongyloides venezuelensis Induced by BnSP- 6, a Lys49-phospholipase A2 Homologue from Bothrops pauloensis Venom


Jéssica Peixoto Rodrigues, Fernanda Van Petten Vasconcelos Azevedo, Mariana Alves Pereira Zoia, Larissa Prado Maia, Lucas Ian Veloso Correia, Julia Maria Costa-Cruz, Veridiana de Melo Rodrigues and Luiz Ricardo Goulart*


DOI: 10.2174/1568026619666190723152520
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Pharmacology of Ivabradine and the Effect on Chronic Heart Failure


Yue Zhou, Jian Wang, Zhuo Meng, Shuang Zhou, Jiayu Peng, Sun Chen, Qingjie Wang* and Kun Sun*


DOI: 10.2174/1568026619666190809093144
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The Use of Conformational Restriction in Medicinal Chemistry


Pedro de Sena M. Pinheiro, Daniel A. Rodrigues, Rodolfo do Couto Maia, Sreekanth Thota and Carlos A. M. Fraga*


DOI: 10.2174/1568026619666190712205025
View Abstract


Virtual Screening Techniques in Drug Discovery: Review and Recent Applications


Sheisi Fonseca Leite da Silva Rocha*, Carolina Gurski Olanda, Harold Hilarion Fokoue and Carlos Mauricio R. Sant`Anna


DOI: 10.2174/1568026619666190816101948
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Molecular Hybridization as a Tool for Designing Multitarget Drug Candidates for Complex Diseases


Viktoriya Ivasiv, Claudia Albertini, Ana Elisa Goncalves, Michele Rossi and Maria Laura Bolognesi*


DOI: 10.2174/1568026619666190619115735
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Unfolded Protein Response as a Therapeutic Target in Cardiovascular Disease


Guangyu Zhang, Xiaoding Wang, Thomas G. Gillette, Yingfeng Deng and Zhao V. Wang*


DOI: 10.2174/1568026619666190521093049
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Editor-in-Chief

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

Biography View Full Editorial Board

Journal History

Current Topics in Medicinal Chemistry was introduced in 2001 with the assistance of Dr. Allen B. Reitz, who is the current Editor-in-Chief serving since 2001.
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Scopus CiteScore Metrics: 1.94


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