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Current Topics in Medicinal Chemistry

Volume 19, 32 Issues, 2019
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access

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  • 18th of 59 in

    Chemistry, Medicinal

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Aims & Scope

Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.

Current Topics in Medicinal Chemistry

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Volume 18

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Number 31



Editorial   Open Access



Review Article



Review Article



Review Article



Review Article

Modern Computational Strategies for Designing Drugs to Curb Human Diseases: A Prospect

, 18(31): 2702 - 2719

Khalid Bashir Dar, Aashiq Hussain Bhat, Shajrul Amin, Rabia Hamid, Suhail Anees, Syed Anjum, Bilal Ahmad Reshi, Mohammad Afzal Zargar, Akbar Masood and Showkat Ahmad Ganie*


DOI: 10.2174/1568026619666190119150741


Research Article



Research Article



Articles Ahead of Print


In Silico Protein Interaction Network Analysis of Virulence Proteins Associated with Invasive Aspergillosis for Drug Discovery


Renu Chaudhary, Meenakshi Balhara, Deepak Kumar Jangir, Mehak Dangi, Mrridula Dangi and Anil K. Chhillar*


View Abstract View on PubMed



Recent Advances in Prostate-Specific Membrane Antigen-Based Radiopharmaceuticals


Wei Diao, Huawei Cai, Lihong Chen, Xi Jin, Xinyang Liao and Zhiyun Jia*


View Abstract View on PubMed




Zinc-dependent Deacetylase (HDAC) Inhibitors with Different ZBG Groups


Yan Li, Fang Wang, Xiaoxue Chen, Jie Wang, Yonglong Zhao, Yongjun Li and Bin He*


View Abstract View on PubMed



Advances in In-silico B-cell Epitope Prediction


Pingping Sun, Sijia Guo, Jiahang Sun, Liming Tan , Chang Lu and Zhiqiang Ma*


View Abstract View on PubMed


Abstracts Ahead of Print




Novel pyrazolo [4, 3-c] quinolin-3-one derivatives as PDE5A inhibitors


Althaf Shaik, Harshit Kumar Agarwal , Rashmi Bhakuni and Sivapriya Kirubakaran*


View Abstract



Design, synthesis, evaluation of antimicrobial activity and docking studies of thiazole-based chalcones.


Christophe Tratrat, Michelyne Haroun, Iakovos Xenikakis, Konstantinos Liaras, Evangelia Tsolaki, Phaedra Eleftheriou, Anthi Petrou, Bandar Aldhubiab, Mahesh Attimarad, Katharigatta N. Venugopala, Sree Harsha, Heba S. Elsewedy, Athina Geronikaki* and Marina Soković


View Abstract



Peptide Sequence-Dominated Enzyme-Responsive Nanoplatform for Anticancer Drug Delivery


Yanan Li , Liping Du, Chunsheng Wu, Bin Yu, Hui Zhang * and Feifei An*


View Abstract


Small molecule natural products and Alzheimer’s disease


Xiaoai Wu, Huawei Cai, Lili Pan, Gang Cui, Feng Qin, YunChun Li and Zhengxin Cai*


View Abstract



Editor's Choice

Parallelization of Molecular Docking: A Review

, 2018; 18(12): 1015 - 1028

Dong Dong, Zhijian Xu, Wu Zhong and Shaoliang Peng*


DOI: 10.2174/1568026618666180821145215




A Review on Plant Antimicrobials of Past Decade

, 2018; 18(10): 812 - 833

Preet Amol Singh, Sapna D. Desai and Jasbir Singh*


DOI: 10.2174/1568026618666180516123229




Prediction and Targeting of Interaction Interfaces in G-protein Coupled Receptor Oligomers

, 2018; 18(8): 714 - 746

Anke C. Schiedel, Meryem Kose, Carlos Barreto, Beatriz Bueschbell, Giulia Morra, Ozge Sensoy* and Irina S. Moreira*


DOI: 10.2174/1568026618666180604082610






Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards

, 2018; 18(4): 256 - 274

Justine P.R. Oliveira*, H. Ivan Melendez-Ortiz, Emilio Bucio, Patricia Terra Alves, Mayara Ingrid Sousa Lima, Luiz Ricardo Goulart, Monica B. Mathor, Gustavo H.C. Varca and Ademar B. Lugao


DOI: 10.2174/1568026618666180410151518



Aurora Kinase Inhibitors in Head and Neck Cancer

, 2018; 18(3): 199 - 213

Guangying Qi, Jing Liu, Sisi Mi, Takaaki Tsunematsu, Shengjian Jin, Wenhua Shao, Tian Liu, Naozumi Ishimaru, Bo Tang* and Yasusei Kudo*


DOI: 10.2174/1568026618666180112163741



Open Access Articles



Treatment of Toxoplasmosis and Neosporosis in Farm Ruminants: State of Knowledge and Future Trends

, 2018; 18(15): 1304 - 1323

Roberto Sánchez-Sánchez, Patricia Vázquez, Ignacio Ferre and Luis Miguel Ortega-Mora*




Mechanical Properties of Composite Hydrogels for Tissue Engineering

, 2018; 18(14): 1214 - 1223

Ramon Rial, J.F. Armando Soltero, Pedro V. Verdes, Zhen Liu and Juan M. Ruso*





Analyzing of Molecular Networks for Human Diseases and Drug Discovery

, 2018; 18(12): 1007 - 1014

Tong Hao, Qian Wang, Lingxuan Zhao, Dan Wu, Edwin Wang* and Jinsheng Sun*




Toward Reproducible Results from Targeted Metabolomic Studies: Perspectives for Data Pre-processing and a Basis for Analytic Pipeline Development

, 2018; 18(11): 883 - 895

Thomas Gross, Mark Mapstone, Ricardo Miramontes, Robert Padilla, Amrita K. Cheema, Fabio Macciardi, Howard J. Federoff* and Massimo S. Fiandaca*





Ubiquitin Proteasome System as a Potential Drug Target for Malaria

, 2018; 18(5): 315 - 320

Pedro H. Scarpelli Pereira, Chiara Curra and Celia R.S. Garcia*




Metabolomics Applications in Precision Medicine: An Oncological Perspective

, 2017; 17(24): 2740 - 2751

Leonor Puchades-Carrasco and Antonio Pineda- Lucena*




InsP3 Signaling in Apicomplexan Parasites

, 2017; 17(19): 2158 - 2165

Celia R.S. Garcia*, Eduardo Alves, Pedro H. S. Pereira, Paula J. Bartlett, Andrew P. Thomas, Katsuhiko Mikoshiba, Helmut Plattner and L. David Sibley









Most Cited Articles







Electronic Nose and Exhaled Breath NMR-based Metabolomics Applications in Airways Disease

, 2016; 16(14): 1610-1630.

Giuseppe Santini, Nadia Mores, Andreu Penas, Rosamaria Capuano, Chiara Mondino, Andrea Trové, Francesco Macagno, Gina Zini, Paola Cattani, Eugenio Martinelli, Andrea Motta, Giuseppe Macis, Giovanni Ciabattoni and Paolo Montuschi


DOI: 10.2174/1568026616666151223113540


Targeting Insulin Signaling for the Treatment of Alzheimer's Disease

, 2016; 16(5): 485-492.

Yanxing Chen, Jianfang Zhang, Baorong Zhang and Cheng-Xin Gong


DOI: 10.2174/1568026615666150813142423






Most Accessed Articles




3D-QSAR in Drug Design - A Review

, 2010; 10(1): 95-115.

Jitender Verma, Vijay M. Khedkar and Evans C. Coutinho


DOI: 10.2174/156802610790232260



Novel Classes of Antibacterial Drugs in Clinical Development, a Hope in a Post-antibiotic Era

, 2018; 18(14): 1188-1202.

J. Campanini-Salinas, J. Andrades-Lagos, J. Mella-Raipan and D. Vasquez-Velasquez*


DOI: 10.2174/1568026618666180816162846



An Update on MDMX and Dual MDM2/X Inhibitors

, 2018; 18(8): 647-660.

Margarida Espadinha, Valentina Barcherini, Elizabeth A. Lopes and Maria M.M. Santos*


DOI: 10.2174/1568026618666180604080119





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