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Current Topics in Medicinal Chemistry

Volume 20, 32 Issues, 2020
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access
Order Your Article Before PrintSubscribe to this Journal

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.

Current Topics in Medicinal Chemistry

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Volume 20

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Number 15



Perspectives in Medicinal Chemistry   Open Access



Editorial   Open Access



Research Article

Differences in Kynurenine Metabolism During Depressive, Manic, and Euthymic Phases of Bipolar Affective Disorder

, 20(15): 1344 - 1352

Alexander Maget, Martina Platzer*, Susanne A. Bengesser, Frederike T. Fellendorf, Armin Birner, Robert Queissner, Carlo Hamm, Bernd Reininghaus, Andrzej Hecker, Lukas Tomberger, Renè Pilz, Nina Dalkner, Natalie Moll, Gregor Schütze, Markus Schwarz, Hans P. Kapfhammer and Eva Z. Reininghaus


DOI: 10.2174/1568026619666190802145128


Review Article

Periodontal Pathogens and Neuropsychiatric Health

, 20(15): 1353 - 1397

Abhishek Wadhawan, Mark A. Reynolds, Hina Makkar, Alison J. Scott, Eileen Potocki, Andrew J. Hoisington, Lisa A. Brenner, Aline Dagdag, Christopher A. Lowry, Yogesh Dwivedi and Teodor T. Postolache*


DOI: 10.2174/1568026620666200110161105


Systematic Review Article



Review Article



Current Topics in Medicinal Chemistry, Volume 20 (2020) - Number 19


This issue is in progress but contains articles that are final and fully citable.

Current Topics in Medicinal Chemistry, Volume 20 (2020) - Number 18


This issue is in progress but contains articles that are final and fully citable.

Current Topics in Medicinal Chemistry, Volume 20 (2020) - Number 17


This issue is in progress but contains articles that are final and fully citable.

Current Topics in Medicinal Chemistry, Volume 20 (2020) - Number 16


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Synthesis and Evaluation of Antimicrobial Activity and Molecular Docking of New N-1,3-thiazol-2-ylacetamides of Condensed Pyrido[3',2':4,5] furo(thieno)[3,2-d]pyrimidines


Sirakanyan S.N.*, Kartsev V.G., Geronikaki A., Spinelli D., Petrou A., Hakobyan E.K., Glamoclija Ja., Ivanov M., Sokovic M. and Hovakimyan A.A.


DOI: 10.2174/1568026620666200628145308
View Abstract View on PubMed




Insights into Nanotherapeutic Strategies as an Impending Approach to Liver Cancer Treatment


Archu Singh, Sadat Shafi, Tanya Upadhyay, Abul Kalam Najmi, Kanchan Kohli and Faheem Hyder Pottoo*


DOI: 10.2174/1568026620666200624161801
View Abstract View on PubMed


Evidence Linking Protein Misfolding to Quality Control in Progressive Neurodegenerative Diseases


Md. Tanvir Kabir, Md. Sahab Uddin*, Ahmed Abdeen, Ghulam Md Ashraf, Asma Perveen, Abdul Hafeez, May N. Bin-Jumah and Mohamed M. Abdel-Daim


DOI: 10.2174/1568026620666200618114924
View Abstract View on PubMed




An Update on Staphylococcus aureus NorA Efflux Pump Inhibitors


Kadja Luana Chagas Monteiro, Thiago Mendonça de Aquino and Francisco Jaime B. Mendonça Junior*


DOI: 10.2174/1568026620666200704135837
View Abstract


Shape-based Machine Learning Models for the potential Novel COVID-19 protease inhibitors assisted by Molecular Dynamics Simulation.


Ravina Khandelwal, Anuraj Nayarisseri*, Maddala Madhavi, Chandrabose Selvaraj, Umesh Panwar, Khushboo Sharma, Tajamul Hussain and Sanjeev Kumar Singh


DOI: 10.2174/1568026620666200704135327
View Abstract



Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Parallelization of Molecular Docking: A Review

, 2018; 18(12): 1015 - 1028

Dong Dong, Zhijian Xu, Wu Zhong and Shaoliang Peng*


DOI: 10.2174/1568026618666180821145215




A Review on Plant Antimicrobials of Past Decade

, 2018; 18(10): 812 - 833

Preet Amol Singh, Sapna D. Desai and Jasbir Singh*


DOI: 10.2174/1568026618666180516123229




Prediction and Targeting of Interaction Interfaces in G-protein Coupled Receptor Oligomers

, 2018; 18(8): 714 - 746

Anke C. Schiedel, Meryem Kose, Carlos Barreto, Beatriz Bueschbell, Giulia Morra, Ozge Sensoy* and Irina S. Moreira*


DOI: 10.2174/1568026618666180604082610






Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards

, 2018; 18(4): 256 - 274

Justine P.R. Oliveira*, H. Ivan Melendez-Ortiz, Emilio Bucio, Patricia Terra Alves, Mayara Ingrid Sousa Lima, Luiz Ricardo Goulart, Monica B. Mathor, Gustavo H.C. Varca and Ademar B. Lugao


DOI: 10.2174/1568026618666180410151518



Aurora Kinase Inhibitors in Head and Neck Cancer

, 2018; 18(3): 199 - 213

Guangying Qi, Jing Liu, Sisi Mi, Takaaki Tsunematsu, Shengjian Jin, Wenhua Shao, Tian Liu, Naozumi Ishimaru, Bo Tang* and Yasusei Kudo*


DOI: 10.2174/1568026618666180112163741



Open Access Articles

Telomere-related Markers for Cancer

, 2020; 20(6): 410 - 432

Xiaotian Yuan*, Mingkai Dai and Dawei Xu*




Peptide Receptor Radionuclide Therapy: Looking Back, Looking Forward

, 2020; 20: 1 - 11 (E-Pub Ahead of Print)

Danny Feijtel, Marion de Jong and Julie Nonnekens*






Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication

, 2019; 19(18): 1621 - 1649

Kenji Maeda*, Debananda Das, Takuya Kobayakawa, Hirokazu Tamamura and Hiroaki Takeuchi*




Targeting the PAC1 Receptor for Neurological and Metabolic Disorders

, 2019; 19(16): 1399 - 1417

Chenyi Liao, Mathilde P. de Molliens, Severin T. Schneebeli, Matthias Brewer, Gaojie Song, David Chatenet, Karen M. Braas, Victor May* and Jianing Li*




Ensemble-Based Modeling of Chemical Compounds with Antimalarial Activity

, 2019; 19(11): 957 - 969

Ana Yisel Caballero-Alfonso, Maykel Cruz-Monteagudo, Eduardo Tejera, Emilio Benfenati, Fernanda Borges, M. Natália D.S. Cordeiro, Vinicio Armijos-Jaramillo and Yunierkis Perez-Castillo*






Treatment of Toxoplasmosis and Neosporosis in Farm Ruminants: State of Knowledge and Future Trends

, 2018; 18(15): 1304 - 1323

Roberto Sánchez-Sánchez, Patricia Vázquez, Ignacio Ferre and Luis Miguel Ortega-Mora*




Mechanical Properties of Composite Hydrogels for Tissue Engineering

, 2018; 18(14): 1214 - 1223

Ramon Rial, J.F. Armando Soltero, Pedro V. Verdes, Zhen Liu and Juan M. Ruso*





Analyzing of Molecular Networks for Human Diseases and Drug Discovery

, 2018; 18(12): 1007 - 1014

Tong Hao, Qian Wang, Lingxuan Zhao, Dan Wu, Edwin Wang* and Jinsheng Sun*




Toward Reproducible Results from Targeted Metabolomic Studies: Perspectives for Data Pre-processing and a Basis for Analytic Pipeline Development

, 2018; 18(11): 883 - 895

Thomas Gross, Mark Mapstone, Ricardo Miramontes, Robert Padilla, Amrita K. Cheema, Fabio Macciardi, Howard J. Federoff* and Massimo S. Fiandaca*






Most Cited Articles


Review Article

Biological activities of artemisinin derivatives beyond malaria

, 2019; 19(3): 205-222.

Xiaoyan Liu, Jianguo Cao, Guozheng Huang*, Qingjie Zhao* and Jingshan Shen


DOI: 10.2174/1568026619666190122144217



Review Article

Nanoparticle therapy for prostate cancer: Overview and perspectives

, 2019; 19(1): 57-73.

Junfu Zhang, Liying Wang, Xinru You, Tuzeng Xian, Jun Wu* and Jun Pang*


DOI: 10.2174/1568026619666190125145836


Review Article

MicroRNAs in cardiovascular disease: Small molecules but big roles

, 2019; 19(21): 1918-1947.

Bingqian Yan, Huijing Wang, Yao Tan and Wei Fu*


DOI: 10.2174/1568026619666190808160241


Review Article

Mycobacterial tuberculosis Enzyme Targets and their Inhibitors

, 2019; 19(5): 337-355.

Anil Kumar Saxena* and Anamika Singh


DOI: 10.2174/1568026619666190219105722


Review Article

Peptide sequence-dominated enzyme-responsive nanoplatform for anticancer drug delivery

, 2019; 19(1): 74-97.

Yanan Li , Liping Du, Chunsheng Wu, Bin Yu, Hui Zhang * and Feifei An*


DOI: 10.2174/1568026619666190125144621


Review Article

Molecular hybridization as a tool for designing multitarget drug candidates for complex diseases

, 2019; 19(19): 1694-1711.

Viktoriya Ivasiv, Claudia Albertini, Ana E. Gonçalves, Michele Rossi and Maria L. Bolognesi*


DOI: 10.2174/1568026619666190619115735


Review Article

STAT3: A potential drug target for tumor and inflammation

, 2019; 19(15): 1305-1317.

Yang Sheng Hu, Xu Han and Xin Hua Liu*


DOI: 10.2174/1568026619666190620145052



Review Article

Zinc-depend ent deacetylase (HDAC) inhibitors with different zinc binding groups

, 2019; 19(3): 223-241.

Yan Li, Fang Wang, Xiaoxue Chen, Jie Wang, Yonglong Zhao, Yongjun Li and Bin He*


DOI: 10.2174/1568026619666190122144949



Perspectives in Medicinal Chemistry

Targeting histone lysine demethylase LSD1/KDM1A as a new avenue for cancer therapy

, 2019; 19(11): 889-891.

Yuan Fang, Guochao Liao* and Bin Yu*


DOI: 10.2174/156802661911190725094910



Review Article

New promises to cure cancer and other genetic diseases/disorders: Epi-drugs through epigenetics

, 2019; 19(12): 972-994.

Yong-Tao Duan, Chetan B. Sangani*, Wei Liu, Kunjal V. Soni and Yongfang Yao*


DOI: 10.2174/1568026619666190603094439



Most Accessed Articles




Progress in Target Drug Molecules for Alzheimer's Disease

, 2020; 20(1): 4-36.

Jiayang Xie, Ruirui Liang, Yajiang Wang, Junyi Huang*, Xin Cao* and Bing Niu*


DOI: 10.2174/1568026619666191203113745




The Present and Future of Novel Protein Degradation Technology

, 2019; 19(20): 1784-1788.

Liwen Xia, Wei Liu, Yinsen Song, Hailiang Zhu* and Yongtao Duan*


DOI: 10.2174/1568026619666191011162955





Editor-in-Chief

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
(USA)
Biography View Full Editorial Board

Journal History

Current Topics in Medicinal Chemistry was introduced in 2001 with the assistance of Dr. Allen B. Reitz, who is the current Editor-in-Chief serving since 2001.

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