Contents

Current Signal Transduction Therapy, Volume 6 - Number 2

Editorial [Hot Topic: Hepatocyte Growth Factor and Its Signalling, New Horizons in Medicine and Therapies (Guest Editors: Wen G. Jiang and Kunio Matsumoto)]

, 6(2): 141 - 142

Wen G. Jiang and Kunio Matsumoto


DOI: 10.2174/157436211795660043




Introduction: Hepatocyte Growth Factor and Met Receptor, from Discovery to Therapeutic Implications

, 6(2): 143 - 145

Toshikazu Nakamura


DOI: 10.2174/157436211795659937




The Hepatocyte Growth Factor Receptor: Structure, Function and Pharmacological Targeting in Cancer

, 6(2): 146 - 151

Fabiola Cecchi, Daniel C. Rabe and Donald P. Bottaro


DOI: 10.2174/157436211795659955




HGF and HGF Agonists, Expression in Wound and Potential Role in the Management of Wound Healing

, 6(2): 152 - 155

Kevin Conway


DOI: 10.2174/157436211795659919




Hepatocyte Growth Factor (HGF): Neurotrophic Functions and Therapeutic Implications for Neuronal Injury/Diseases

, 6(2): 156 - 167

Hiroshi Funakoshi and Toshikazu Nakamura


DOI: 10.2174/157436211795659982




Hepatocyte Growth Factor is a Potential Lymphangiogenic Factor; Clinical Implications

, 6(2): 168 - 172

Wen G. Jiang and Andrew J. Sanders


DOI: 10.2174/157436211795659900




HGF and RhoGTPases in Cancer Cell Motility

, 6(2): 173 - 179

Jane Lane, Tracey A. Martin and Wen G. Jiang


DOI: 10.2174/157436211795660052




Hepatocyte Growth Factor Signaling in Cancer Metastasis

, 6(2): 180 - 190

Tracey A. Martin, Malcolm D. Mason and Wen G. Jiang


DOI: 10.2174/157436211795659991




HGF-Antagonists: Structure, Activities, and Anti-cancer Approach

, 6(2): 191 - 199

Katsuya Sakai, Takahiro Nakamura, Takayoshi Kinoshita, Toshikazu Nakamura and Kunio Matsumoto


DOI: 10.2174/157436211795659964




Hepatocyte Growth Factor (HGF) for a Cell-Signal-Based Therapy During Acute and Chronic Liver Diseases

, 6(2): 200 - 209

Kiyomasa Oka, Kazuhiro Fukuta and Shinya Mizuno


DOI: 10.2174/157436211795659973




Hepatocyte Growth Factor (HGF), an Endogenous Pulmotrophic Regulator, for the Rescue of Acute and Chronic Lung Diseases

, 6(2): 210 - 220

Shinya Mizuno, Hiroyuki Ohnishi and Toshikazu Nakamura


DOI: 10.2174/157436211795659946




HGF as Angiogenic Factor and Therapeutic Approach

, 6(2): 221 - 227

Yoshiaki Taniyama, Yasushi Takeya, Junya Azuma, Kazuma Iekushi, Fumihiro Sanada, Hiroshi Kusunoki, Keita Okayama, Nobutaka Koibuchi, Hiromi Rakugi and Ryuichi Morishita


DOI: 10.2174/157436211795660016




HGF-MET in Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer

, 6(2): 228 - 233

Seiji Yano, Wei Wang, Qi Li, Tadaaki Yamada, Shinji Takeuchi, Kunio Matsumoto, Yasuhiko Nishioka and Saburo Sone


DOI: 10.2174/157436211795659928




Editorial [Hot Topic: Towards Tailored Treatment - New Organ-Specific Drug Strategies Interfering in Signal Transduction (Guest Editors: Jai Prakash and Martin H. de Borst)]

, 6(2): 234 - 236

Jai Prakash and Martin H. de Borst


DOI: 10.2174/157436211795660025




Pharmacological Strategies that Affect HIF-1 in the Ischemic Brain: Focus on Hydroxylases Activity and Protein Kinase Pathways

, 6(2): 237 - 248

Maria Elena Chanez-Cardenas, Monica Espinoza-Rojo, Jose A. Rivera-Rodriguez and Penelope Aguilera


DOI: 10.2174/157436211795660061




Targeted Renal Delivery of Protein Kinase Inhibitors for the Treatment of Chronic Kidney Disease

, 6(2): 249 - 259

Fariba Poosti, Jan-Luuk Hillebrands, van Goor van Goor and Martin H. de Borst


DOI: 10.2174/157436211795659892




New Organ-Specific Drug Strategies Interfering in Signaling Pathways: Kinase Inhibitors and Other New Developmental Drugs in HCC

, 6(2): 260 - 266

Fabio Farinati, Nora Cazzagon, Anna Giacomin and Anna


DOI: 10.2174/157436211795660034




Targeted Delivery of Kinase Inhibitors: A Nanomedicine Approach for Improved Selectivity in Cancer

, 6(2): 267 - 278

Isil Altintas, Raymond Schiffelers and Robbert Jan Kok


DOI: 10.2174/157436211795660007




New Organ-Specific Pharmacological Strategies Interfering With Signaling Pathways In Inflammatory Disorders/Autoimmune Disorders

, 6(2): 279 - 291

Bradley A. Wisler, James E. Dennis and Charles J. Malemud


DOI: 10.2174/157436211795659883




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