Contents

Current Signal Transduction Therapy, Volume 6 - Number 1

Preface

, 6(1): 1

Gyorgy Keri and Axel Ullrich


DOI: 10.2174/157436211794109442




Small Molecules in Cancer Therapy: Cytotoxics and Molecularly Targeted Agents

, 6(1): 2 - 19

Anna Blazovics


DOI: 10.2174/157436211794109451




Leptin Signaling in Blood Platelets as a Target for Therapeutic Intervention

, 6(1): 20 - 28

Jerzy Beltowski


DOI: 10.2174/157436211794109415




Inhibition of TGF- Signaling for the Treatment of Tumor Metastasis and Fibrotic Diseases

, 6(1): 29 - 43

Ota Fuchs


DOI: 10.2174/157436211794109398




Promising Activity of Mammalian Target of Rapamycin Inhibitors in Hematologic Malignancies Therapy

, 6(1): 44 - 54

Ota Fuchs


DOI: 10.2174/157436211794109460




Putative Breast Tumor Suppressor TACC2 Suppresses the Aggressiveness of Breast Cancer Cells through a PLCγ Pathway

, 6(1): 55 - 64

Shan Cheng, Tracey A. Martin, Xu Teng and Wen G. Jiang


DOI: 10.2174/157436211794109361




Multiplex Analysis of Cardiac Hypertrophic Signaling: Reduced in vivo Phosphorylation of Glycogen Synthase Kinase-3β and Proline-Rich Akt Substrate (PRAS40)

, 6(1): 65 - 70

Jens R. Larsen, Morten Smerup, Rikke Norregaard, Jane H. Christensen, Kim Sivesgaard, Sara D. Christensen, Karin Christensen, Erik Sloth, Peter Torp, Niels Gregersen and J. Michael Hasenkam


DOI: 10.2174/157436211794109406




Dystroglycan, A Multifunctional Adaptor Protein for Signal Transduction and A Potential Therapeutic Target

, 6(1): 71 - 81

Hiroki Hagiwara and Kiichiro Matsumura


DOI: 10.2174/157436211794109424




Balance Between S6K-S6 and 4E-BP1 Depends on ERK Activity in Developing Neurons

, 6(1): 82 - 87

Ichiro Nishimura, Kanji Mori, Yoshitaka Matsusue, Hidetoshi Okabe and Tokuhiro Chano


DOI: 10.2174/157436211794109343




Serine-Threonine Protein Kinases CK1, CK2 and GSK3 in Normal and Malignant Haematopoiesis

, 6(1): 88 - 98

Francesco Piazza, Sabrina Manni, Anna Colpo, Laura Quotti Tubi, Carmela Gurrieri and Gianpietro Semenzato


DOI: 10.2174/157436211794109370




Dasatinib in the Treatment of Chronic Myeloid Leukemia

, 6(1): 99 - 105

Joanna Gora-Tybor and Tadeusz Robak


DOI: 10.2174/157436211794109352




Molecular Mechanisms of Action of Gas1 and its Possible Therapeutic Applications

, 6(1): 106 - 112

Gabriela Dominguez-Monzon, Ricardo Gonzalez-Ramirez and Jose Segovia


DOI: 10.2174/157436211794109433




Identification of Phosphoproteins and their Impact as Biomarkers in Cancer Therapeutics

, 6(1): 113 - 140

Samantha M. Frawley Cass and Jetze J. Tepe


DOI: 10.2174/157436211794109389




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