Contents

Current Pharmaceutical Design, Volume 8 - Number 25

Preface

, 8(25): i

Lesley K Seymour


DOI: 10.2174/1381612023393035




Rationale for Ras and Raf-kinase as a Target for Cancer Therapeutics

, 8(25): 2231 - 2242

Michelle Nottage and Lillian L. Siu


DOI: 10.2174/1381612023393107




Inhibition of Raf Kinase in the Treatment of Acute Myeloid Leukemia

, 8(25): 2243 - 2248

Michael Crump


DOI: 10.2174/1381612023393008




BAY 43-9006: Early Clinical Data in Patients with Advanced Solid Malignancies

, 8(25): 2249 - 2253

Sebastien J. Hotte and Hal W. Hirte


DOI: 10.2174/1381612023393053




BAY 43-9006: Preclinical Data

, 8(25): 2255 - 2257

Scott Wilhelm and Du-Shieng Chien


DOI: 10.2174/1381612023393026




Agents Targeting Ras Signaling Pathway

, 8(25): 2259 - 2267

J. E. Dancey


DOI: 10.2174/1381612023393071




Design and Discovery of Small Molecules Targeting Raf-1 Kinase

, 8(25): 2269 - 2278

Timothy B. Lowinger, Bernd Riedl, Jacques Dumas and Roger A. Smith


DOI: 10.2174/1381612023393125




The Design of Clinical Trials for New Molecularly Targeted Compounds: Progress and New Initiatives

, 8(25): 2279 - 2284

Lesley Seymour


DOI: 10.2174/1381612023393099




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