Contents

Current Pharmaceutical Design, Volume 6 - Number 18

Preface

, 6(18): i

Alan P. Kozikowski and Pier G. Baraldi


DOI: 10.2174/1381612003398636




Structure-based Design of Compounds Inhibiting Grb2-SH2 Mediated Protein-protein Interactions in Signal Transduction Pathways

, 6(18): 1777 - 1796

H. Fretz, P. Furet, C. Garcia-Echeverria, J. Rahuel and J. Schoepfer


DOI: 10.2174/1381612003398546




From a Classic Approach in Cancer Chemotherapy Towards Differentiation Therapy: Acyclic and Cyclic Seven-Membered 5-Fluorouracil O,N-Acetals

, 6(18): 1797 - 1810

J. Campos, J. F. Dominguez, M. A. Gallo and A. Espinosa


DOI: 10.2174/1381612003398627




Antitumor Properties of Podophyllotoxin and Related Compounds

, 6(18): 1811 - 1839

M. Gordaliza, M. A. Castro, J. M. Miguel del Corral and A. San Feliciano


DOI: 10.2174/1381612003398582




Understanding and Exploiting Natures Chemical Arsenal: The Past,Present and Future of Calicheamicin Research

, 6(18): 1841 - 1879

Jon S. Thorson, Eric L. Sievers, Joachim Ahlert, Erica Shepard, Ross E. Whitwam, Kenolisa C. Onwueme and Mark Ruppen


DOI: 10.2174/1381612003398564




Mucins in the Diagnosis and Therapy of Pancreatic Cancer

, 6(18): 1881 - 1896

Jenny J. L. Ho


DOI: 10.2174/1381612003398609




Fibroblast Growth Factors and Their Inhibitors

, 6(18): 1897 - 1924

F. Manetti, F. Corelli and M. Botta


DOI: 10.2174/1381612003398528




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