Contents

Current Pharmaceutical Design, Volume 23 - Number 38

Editorial

Editorial: Neonatal Clinical Pharmacology: A Rapidly Maturing Discipline

, 23(38): 5767 - 5768

Karel Allegaert and John N van den Anker


DOI: 10.2174/138161282338180209180957




Review Article

Developmental Pharmacokinetics in Neonates: Maturational Changes and Beyond

, 23(38): 5769 - 5778

Karel Allegaert*, Paola Mian and John N. van den Anker


DOI: 10.2174/1381612823666170926121124




Review Article

Age-Appropriate Formulations Including Pharmaceutical Excipients in Neonatal Medicines

, 23(38): 5779 - 5789

Karin Kogermann, Jana Lass, Georgi Nellis, Tuuli Metsvaht and Irja Lutsar*


DOI: 10.2174/1381612823666170926122613




Review Article

Therapeutic Drug Monitoring in Neonates: What Makes them Unique?

, 23(38): 5790 - 5800

P. Mian*, R. B. Flint, D. Tibboel, J. N. van den Anker, K. Allegaert and B. C.P. Koch


DOI: 10.2174/1381612823666170926143820




Review Article

Collaboration in Regulatory Science to Facilitate Therapeutic Development for Neonates

, 23(38): 5801 - 5804

Susan K. McCune*, Yeruk Ager Mulugeta and Gerri R. Baer


DOI: 10.2174/1381612823666170926114857




Review Article

Optimising β -lactam Dosing in Neonates: A Review of Pharmacokinetics, Drug Exposure and Pathogens

, 23(38): 5805 - 5838

Aline Fuchs*, Grace Li, Johannes N. van den Anker and Julia Bielicki


DOI: 10.2174/1381612823666170925162143




Review Article

Intravenous Paracetamol Dosing Guidelines for Pain Management in (pre)term Neonates Using the Paediatric Study Decision Tree

, 23(38): 5839 - 5849

P. Mian*, C. A.J. Knibbe, E. A.M. Calvier, D. Tibboel and K. Allegaert


DOI: 10.2174/1381612823666170921143104




Review Article

Cardiovascular Drug Therapy for Human Newborn: Review of Pharmacodynamic Data

, 23(38): 5850 - 5860

Ebru Ergenekon, Héctor Rojas-Anaya, María Carmen Bravo, Charalampos Kotidis, Liam Mahoney and Heike Rabe*


DOI: 10.2174/1381612823666170918122755




Review Article

Neonatal Pain, Still Searching for the Optimal Approach

, 23(38): 5861 - 5878

Elizabeth Walter-Nicolet*, Laurent Calvel*, Geraldine Gazzo, Pierrick Poisbeau and Pierre Kuhn


DOI: 10.2174/1381612823666171017164957




Review Article

Long-term Effects of Early Exposure to Stress, Pain, Opioids and Anaesthetics on Pain Sensitivity and Neurocognition

, 23(38): 5879 - 5886

Gerbrich E. van den Bosch, Monique van Dijk, Dick Tibboel and Jurgen C. de Graaff*


DOI: 10.2174/1381612823666170926150259




Review Article

Modelling Bronchopulmonary Dysplasia in Animals: Arguments for the Preterm Rabbit Model

, 23(38): 5887 - 5901

Thomas Salaets, Andre Gie, Bieke Tack, Jan Deprest and Jaan Toelen*


DOI: 10.2174/1381612823666170926123550




Review Article

Neonatal Plasticity of the Nociceptive System: Mechanisms, Effects, and Treatment of Repetitive Painful Procedures During NICU Admittance

, 23(38): 5902 - 5910

N. J. van den Hoogen*, J. Patijn, D. Tibboel and E. A. Joosten


DOI: 10.2174/1381612823666170921130320




Review Article

A Human Proximal Tubular Epithelial Cell Model to Explore a Knowledge Gap on Neonatal Drug Disposition

, 23(38): 5911 - 5918

Ahmed Reda*, Anke Raaijmakers, Saskia van Dorst, Charlotte G.G.M. Pauwels, Karel Allegaert, Mohamed A Elmonem, Rosalinde Masereeuw, Lambertus van den Heuvel, Elena Levtchenko and Fanny Oliveira Arcolino*


DOI: 10.2174/1381612823666171009143146




Review Article

Big Data Analyses for Continuous Evaluation of Pharmacotherapy: A Proof of Principle with Doxapram in Preterm Infants

, 23(38): 5919 - 5927

Robert B. Flint*, Willem van Weteringen, Swantje Völler, Jarinda A. Poppe, Birgit C.P. Koch, Ronald de Groot, Dick Tibboel, Catherijne A.J. Knibbe, Irwin K.M. Reiss, Sinno H.P. Simons and DINO Research group


DOI: 10.2174/1381612823666170918121556




Review Article

Aerosol: A Novel Vehicle for Pharmacotherapy in Neonates

, 23(38): 5928 - 5934

Ronan MacLoughlin*, Colin Telfer, Andy Clark and James Fink


DOI: 10.2174/1381612823666170918122136




Review Article

Allopurinol: Old Drug, New Indication in Neonates?

, 23(38): 5935 - 5942

Kim V. Annink, Axel R. Franz, Jan B. Derks, Mario Rüdiger, Frank van Bel and Manon J.N.L. Benders*


DOI: 10.2174/1381612823666170918123307




Review Article

PBPK in Preterm and Term Neonates: A Review

, 23(38): 5943 - 5954

Robin Michelet*, Jan Van Bocxlaer and An Vermeulen


DOI: 10.2174/1381612823666171009143840




Review Article

The Use of Hemodynamic and Cerebral Monitoring to Study Pharmacodynamics in Neonates

, 23(38): 5955 - 5963

A. Smits, L. Thewissen, A. Dereymaeker, E. Dempsey, A. Caicedo and G. Naulaers*


DOI: 10.2174/1381612823666170918124419




Review Article

IGF-1 as a Drug for Preterm Infants: A Step-Wise Clinical Development

, 23(38): 5964 - 5970

Ann Hellström*, David Ley, Boubou Hallberg, Chatarina Löfqvist, Ingrid Hansen-Pupp, Luca A. Ramenghi, Jan Borg, Lois E. H. Smith and Anna-Lena Hard


DOI: 10.2174/1381612823666171002114545




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