Contents

Current Pharmaceutical Design, Volume 23 - Number 14

Editorial

Editorial: (Pharmaco)Metabolomics in Drug Discovery and Individualisation of Treatment

, 23(14): 2027

Theodora Katsila and George P. Patrinos


DOI: 10.2174/1381612823999170301112648




Review Article

Pharmacogenetics and Metabolism from Science to Implementation in Clinical Practice: The Example of Dihydropyrimidine Dehydrogenase

, 23(14): 2028 - 2034

Marzia Del Re, Giuliana Restante, Antonello Di Paolo, Stefania Crucitta, Eleonora Rofi and Romano Danesi


DOI: 10.2174/1381612823666170125155530




Review Article

In vivo Phenotyping Methods: Cytochrome P450 Probes with Emphasis on the Cocktail Approach

, 23(14): 2035 - 2049

Guillermo Alberto Keller, María Laura Ferreirós Gago, Roberto Alejandro Diez and Guillermo Di Girolamo


DOI: 10.2174/1381612823666170207100724




Review Article

Metabolomics in the Diagnosis and Pharmacotherapy of Lung Diseases

, 23(14): 2050 - 2059

Philippe Devillier, Helene Salvator, Emmanuel Naline, Louis-Jean Couderc and Stanislas Grassin-Delyle


DOI: 10.2174/1381612823666170130155627




Review Article

CYP4Z1 – A Human Cytochrome P450 Enzyme that Might Hold the Key to Curing Breast Cancer

, 23(14): 2060 - 2064

Xu Yang, Michael Hutter, Wilson Wen Bin Goh and Matthias Bureik


DOI: 10.2174/1381612823666170207150156




Review Article

Role of Proinflammatory Cytokines in Dopaminergic System Disturbances, Implications for Anhedonic Features of MDD

, 23(14): 2065 - 2072

Zihang Pan, Joshua D. Rosenblat, Walter Swardfager and Roger S. McIntyre


DOI: 10.2174/1381612823666170111144340




Review Article

Selective Inhibition of Phosphodiesterases 4A, B, C and D Isoforms in Chronic Respiratory Diseases: Current and Future Evidences

, 23(14): 2073 - 2083

Sonia Contreras, Javier Milara, Esteban Morcillo and Julio Cortijo


DOI: 10.2174/1381612823666170214105651




Review Article

Biofilm-mediated Antibiotic-resistant Oral Bacterial Infections: Mechanism and Combat Strategies

, 23(14): 2084 - 2095

Indulata Kanwar, Abhishek K. Sah and Preeti K. Suresh


DOI: 10.2174/1381612822666161124154549




Review Article

Cyclodextrins as Complexation Agents to Improve the Anti-inflammatory Drugs Profile: a Systematic Review and Meta-Analysis

, 23(14): 2096 - 2107

Priscila L. Santos, Renan G. Brito, Jullyana S.S. Quintans, Adriano A.S. Araujo, Irwin R.A. Menezes, Nicole K. Brogden and Lucindo J. Quintans-Junior


DOI: 10.2174/1381612823666170126121926




Review Article

Introduction for Design of Nanoparticle Based Drug Delivery Systems

, 23(14): 2108 - 2112

Jun Yan Chan Edgar and Hui Wang


DOI: 10.2174/1381612822666161025154003




Review Article

Anti-EGFRvIII Chimeric Antigen Receptor-Modified T Cells for Adoptive Cell Therapy of Glioblastoma

, 23(14): 2113 - 2116

Pei-pei Ren, Ming Li, Tian-fang Li and Shuang-yin Han


DOI: 10.2174/1381612823666170316125402




Review Article

Discovery and Optimization of NAD+-Dependent DNA Ligase Inhibitors as Novel Antibacterial Compounds

, 23(14): 2117 - 2130

Fangchao Bi, Ruixin Ma and Shutao Ma


DOI: 10.2174/1381612822666161025145639




Research Article

Macrocyclic Antimicrobial Peptides Engineered from ω-Conotoxin

, 23(14): 2131 - 2138

Xinya Hemu and James P. Tam


DOI: 10.2174/1381612822666161027120518




Research Article

Dendritic Cells Modulate Iron Homeostasis and Inflammatory Abilities Following Quercetin Exposure

, 23(14): 2139 - 2146

Vanessa Galleggiante, Stefania De Santis, Elisabetta Cavalcanti, Aurelia Scarano, Maria De Benedictis, Grazia Serino, Maria Lucia Caruso, Mauro Mastronardi, Aldo Pinto, Pietro Campiglia, Dale Kunde, Angelo Santino and Marcello Chieppa


DOI: 10.2174/1381612823666170112125355




Research Article

In Vitro Screening of an FDA-Approved Library Against ESKAPE Pathogens

, 23(14): 2147 - 2157

Waleed Younis, Ahmed AbdelKhalek, Abdelrahman S. Mayhoub and Mohamed N. Seleem


DOI: 10.2174/1381612823666170209154745




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