Contents

Current Pharmaceutical Design, Volume 22 - Number 46

Editorial

Editorial (Thematic Issue: Towards the Integration of Quantitative and Systems Pharmacology into Drug Discovery: a Systems Level Understanding of Therapeutic and Toxic Effects of Drugs)

, 22(46): 6881 - 6884

Violeta I. Perez Nueno


DOI: 10.2174/138161282246170124192058




Review Article

Modeling Polypharmacological Profiles by Affinity Fingerprinting

, 22(46): 6885 - 6894

Agnes Peragovics, Zoltan Simon, Andras Malnasi-Csizmadia and Andreas Bender


DOI: 10.2174/1381612822666160831104718




Review Article

In Silico Systems Pharmacology to Assess Drug's Therapeutic and Toxic Effects

, 22(46): 6895 - 6902

Alejandro Aguayo-Orozco, Karine Audouze, Soren Brunak and Olivier Taboureau


DOI: 10.2174/1381612822666160907093215




Review Article

From PK/PD to QSP: Understanding the Dynamic Effect of Cholesterol-Lowering Drugs on Atherosclerosis Progression and Stratified Medicine

, 22(46): 6903 - 6910

Cesar Pichardo-Almarza and Vanessa Diaz-Zuccarini


DOI: 10.2174/1381612822666160905095402




Review Article

Systems Toxicology: Systematic Approach to Predict Toxicity

, 22(46): 6911 - 6917

Narsis A. Kiani, Ming-Mei Shang and Jesper Tegner


DOI: 10.2174/1381612822666161003115629




Review Article

Current Trends in Drug Sensitivity Prediction

, 22(46): 6918 - 6927

Isidro Cortes-Ciriano, Lewis H. Mervin and Andreas Bender


DOI: 10.2174/1381612822666161026154430




Review Article

Predictive Modeling of Ocular Pharmacokinetics and Adverse Effects

, 22(46): 6928 - 6934

Leo Ghemtio, Henri Xhaard, Arto Urtti and Heidi Kidron


DOI: 10.2174/1381612822666160923120244




Review Article

Polypharmacology in Precision Oncology: Current Applications and Future Prospects

, 22(46): 6935 - 6945

Albert A. Antolin, Paul Workman, Jordi Mestres and Bissan Al-Lazikani


DOI: 10.2174/1381612822666160923115828




Review Article

MiR 221/222 as New Players in Tamoxifen Resistance

, 22(46): 6946 - 6955

Nafiseh Sadat Alamolhodaei, Javad Behravan, Fatemeh Mosaffa and Gholamreza Karimi


DOI: 10.2174/1381612822666161102100211




Review Article

Photosensitizers for Photodynamic Therapy: Photochemistry in the Service of Oncology

, 22(46): 6956 - 6974

Carsten Lange and Patrick J. Bednarski


DOI: 10.2174/1381612822666161124155344




Research Article

Study in Treatment of Collagen-Induced Arthritis in DBA/1 Mice Model by Genistein

, 22(46): 6975 - 6981

Yiping Hu, Jinchao Li, Ling Qin, Wenxiang Cheng, Yuxiao Lai, Ye Yue, Peigen Ren, Xiaohua Pan and Peng Zhang


DOI: 10.2174/1381612822666161025150403




Research Article

Structural Modifications of Diarylpyrimidine-quinolone Hybrids as Potent HIV-1 NNRTIs with an Improved Drug Resistance Profile

, 22(46): 6982 - 6987

Tian-Qi Mao, Qiu-Qin He, Wen-Xue Chen, Gang-Feng Tang, Fen-Er Chen, Erik De Clercq, Dirk Daelemans and Christophe Pannecouque


DOI: 10.2174/1381612823666161122125657




Research Article

Ester-Based Hydrophilic Cyclodextrin Nanosponges for Topical Ocular Drug Delivery

, 22(46): 6988 - 6997

Zikhona Hayiyana, Yahya E. Choonara, Aubrey Makgotloe, Lisa C. du Toit, Pradeep Kumar and Viness Pillay


DOI: 10.2174/1381612822666161216113207




Acknowledgement

ACKNOWLEDGEMENT TO REVIEWERS

, 22(46): 6998


DOI: 10.2174/138161282246170124203633




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