Contents

Current Pharmaceutical Design, Volume 22 - Number 38

Editorial

Editorial (Thematic Issue: Measurements of ABC Transporters at the Blood-Brain Barrier: Novel Methods and Applications)

, 22(38): 5767

Gert Luurtsema


DOI: 10.2174/1381612822666160921102333




Review Article

In Vitro and Ex Vivo Model Systems to Measure ABC Transporter Activity at the Blood-Brain Barrier

, 22(38): 5768 - 5773

Nienke M. de Wit, Gijs Kooij and Helga E. de Vries


DOI: 10.2174/1381612822666160810145536




Review Article

Design and Synthesis of New Selective P-gp Substrates and Inhibitors

, 22(38): 5774 - 5778

Mariangela Cantore, Marcello Leopoldo, Francesco Berardi, Roberto Perrone and Nicola Antonio Colabufo


DOI: 10.2174/1381612822666160810114008




Review Article

PET Tracers for Imaging of ABC Transporters at the Blood-Brain Barrier: Principles and Strategies

, 22(38): 5779 - 5785

Gert Luurtsema, Philip Elsinga, Rudi Dierckx, Ronald Boellaard and Aren van Waarde


DOI: 10.2174/1381612822666160810123634




Review Article

Kinetic Models for Measuring P-glycoprotein Function at the Blood-Brain Barrier with Positron Emission Tomography

, 22(38): 5786 - 5792

Mark Lubberink


DOI: 10.2174/1381612822666160804093852




Review Article

ABC Transporters and Drug Resistance in Patients with Epilepsy

, 22(38): 5793 - 5807

Maria Feldmann and Matthias Koepp


DOI: 10.2174/1381612822666160810150416




Review Article

Blood-Brain Barrier ABC-transporter P-glycoprotein in Alzheimer's Disease: Still a Suspect?

, 22(38): 5808 - 5816

Danielle M.E. van Assema and Bart N.M. van Berckel


DOI: 10.2174/1381612822666160804094544




Review Article

Importance of ABC Transporters in Drug Development

, 22(38): 5817 - 5829

Marcel Benadiba and Yehoshua Maor


DOI: 10.2174/1381612822666160810120359




Review Article

Importance of P-gp PET Imaging in Pharmacology

, 22(38): 5830 - 5836

Jun Toyohara


DOI: 10.2174/1381612822666160804092258




Review Article

Neuronutrient Amino-Acid Therapy Protects Against Reward Deficiency Syndrome: Dopaminergic Key to Homeostasis and Neuroplasticity

, 22(38): 5837 - 5854

Kenneth Blum, Marcelo Febo, Rajendra D. Badgaiyan, Eric R. Braverman, Kristina Dushaj, Mona Li and Zsolt Demetrovics


DOI: 10.2174/1381612822666160719111346




Review Article

Shear Stress-sensitive Carriers for Localized Drug Delivery

, 22(38): 5855 - 5867

Yu Xia, Chun-Yang Shi, Wei Xiong, Xiao-Long Hou, Jian-Guo Fang and Wen-Qing Wang


DOI: 10.2174/1381612822666160628081419




Research Article

Site-Specific Thiol-mediated PEGylation of Streptokinase Leads to Improved Properties with Clinical Potential

, 22(38): 5868 - 5878

Pooja Sawhney, Shekhar Kumar, Neeraj Maheshwari, Sumeet Singh Guleria, Neelam Dhar, Radhika Kashyap and Girish Sahni


DOI: 10.2174/1381612822666160204120547




Research Article

Insulin-Like Growth Factor-1, a Potential Predicative Biomarker for Postoperative Delirium Among Elderly Patients with Open Abdominal Surgery

, 22(38): 5879 - 5883

Huachun Shen, Yi Shao, Junping Chen and Jianrong Guo


DOI: 10.2174/1381612822666160813234311




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