Contents

Current Pharmaceutical Design, Volume 22 - Number 33

Editorial

Editorial (Thematic Issue: Chemoinformatics Models for Pharmaceutical Design, Part 1)

, 22(33): 5041 - 5042

Humberto González-Díaz, Anuraj Nayarisseri, Danail Bonchev and Subhash C. Basak


DOI: 10.2174/138161282233161109224932




Review Article

Probing the Hypothesis of SAR Continuity Restoration by the Removal of Activity Cliffs Generators in QSAR

, 22(33): 5043 - 5056

Maykel Cruz-Monteagudo, José L. Medina-Franco, Yunier Perera-Sardiña, Fernanda Borges, Eduardo Tejera, Cesar Paz-y-Miño, Yunierkis Pérez-Castillo, Aminael Sánchez-Rodríguez, Zuleidys Contreras-Posada and M. Natália D. S. Cordeiro


DOI: 10.2174/1381612822666160509124337




Review Article

De Novo Design of New Inhibitor of Mutated Tyrosine-Kinase for the Myeloid Leukemia Treatment

, 22(33): 5057 - 5064

Washington Pereira and Ihosvany Camps


DOI: 10.2174/1381612822666160607220532




Review Article

How the Protein Architecture of RNases III Influences their Substrate Specificity?

, 22(33): 5065 - 5071

Guillermin Agüero-Chapin, Gisselle Pérez-Machado, Juan Collí Mull, Evys Ancede-Gallardo, Agostinho Antunes and Gustavo A. de la Riva de la Riva


DOI: 10.2174/1381612822666160511150416




Review Article

Common SAR Derived from Multiple QSAR Models on Vorinostat Derivatives Targeting HDACs in Tumor Treatment

, 22(33): 5072 - 5078

Sugathan Praseetha, Srinivas Bandaru, Mukesh Yadav, Anuraj Nayarisseri and Sivanpillai Sureshkumar


DOI: 10.2174/1381612822666160621094009




Review Article

Detection of Quinolone Resistance in Salmonella typhimurium Pig Isolates Determined by gyrA Gene Mutation Using PCR- and Sequence-Based Techniques within the gyrA Gene

, 22(33): 5079 - 5084

Guadalupe Patricia Macías Farrera, Esvieta Tenorio Borroto, Fabiola Rivera Ramírez, Juan Carlos Vázquez Chagoyán, Martín Talavera Rojas, Gilberto Yong Angel and Roberto Montes de Oca Jimenez


DOI: 10.2174/1381612822666160803165645




Review Article

Prediction of Aquatic Toxicity of Benzene Derivatives to Tetrahymena pyriformis According to OECD Principles

, 22(33): 5085 - 5094

Juan A. Castillo-Garit, Concepción Abad, Gerardo M. Casañola-Martin, Stephen Jones Barigye, Francisco Torrens and Amparo Torreblanca


DOI: 10.2174/1381612822666160804095107




Review Article

Generalized Molecular Descriptors Derived From Event-Based Discrete Derivative

, 22(33): 5095 - 5113

Oscar Martínez-Santiago, Reisel Millán Cabrera, Yovani Marrero-Ponce, Stephen J. Barigye, Huong Le-Thi-Thu, F. Javier Torres, Cesar H. Zambrano, Ivan Yaber-Goenaga, Maykel Cruz-Monteagudo, Yoan Martínez López, Facundo Pérez Giménez and Francisco Torrens


DOI: 10.2174/1381612822666160610114148




Review Article

Experimental-Theoretic Approach to Drug-Lymphocyte Interactome Networks with Flow Cytometry and Spectral Moments Perturbation Theory

, 22(33): 5114 - 5119

Esvieta Tenorio-Borroto, Fabiola Rivera Ramírez, Juan Carlos Vazquez Chagoyan, Roberto Montes de Oca Jimenez, Xerardo Garcia-Mera and Humberto Gonzalez-Diaz


DOI: 10.2174/1381612822666160805164308




Review Article

Current Status of Ethosomes and Elastic Liposomes in Dermal and Transdermal Drug Delivery

, 22(33): 5120 - 5126

Kevin Ita


DOI: 10.2174/1381612822666160511150228




Review Article

Role of Colloidal Drug Delivery Carriers in Taxane-mediated Chemotherapy: A Review

, 22(33): 5127 - 5143

Pramod Kumar, Kaisar Raza, Lokesh Kaushik, Ruchi Malik, Shweta Arora and Om Prakash Katare


DOI: 10.2174/1381612822666160524144926




Review Article

The Novel Antipsychotic Cariprazine (RGH-188): State-of-the-Art in the Treatment of Psychiatric Disorders

, 22(33): 5144 - 5162

Domenico De Berardis, Laura Orsolini, Felice Iasevoli, Emiliano Prinzivalli, Andrea de Bartolomeis, Nicola Serroni, Monica Mazza, Alessandro Valchera, Michele Fornaro, Roberta Vecchiotti, Alessandro Carano, Gianna Sepede, Federica Vellante, Ilaria Matarazzo, Maurizio Pompili, Giampaolo Perna, Chiara Conti, Cristina Segura-García, Giovanni Martinotti and Massimo Di Giannantonio


DOI: 10.2174/1381612822666160701084447




Review Article

Development of Antithrombotic Aptamers: From Recognizing Elements to Drugs

, 22(33): 5163 - 5176

Elena Zavyalova, Andrey Golovin, Galina Pavlova and Alexey Kopylov


DOI: 10.2174/1381612822666161004163409




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