Contents

Current Pharmaceutical Design, Volume 22 - Number 14

Editorial

Editorial (Thematic Issue: Effective and Promising Treatments for Neurological Disorders and Cancer)

, 22(14): 1979 - 1980

Victor V. Uteshev


DOI: 10.2174/1381612822999160217154925




Obstacles and Opportunities for Cholinergic Drug Development in the Treatment of Cognitive Disorders

, 22(14): 1981 - 1985

Rachel A. Schroeder, Lynn Wecker and Rex M. Philpot


DOI: 10.2174/1381612822666160127111453




Allosteric Modulation of Nicotinic Acetylcholine Receptors: The Concept and Therapeutic Trends

, 22(14): 1986 - 1997

Victor V. Uteshev


DOI: 10.2174/1381612822666160201115341




Regulation of Gait and Balance: The Underappreciated Role of Neuronal Nicotinic Receptor Agonists

, 22(14): 1998 - 2003

Michael F. Young and Lynn Wecker


DOI: 10.2174/1381612822666160127111848




Role of Nicotinic and Muscarinic Receptors on Synaptic Plasticity and Neurological Diseases

, 22(14): 2004 - 2014

Marco Fuenzalida, Miguel Ángel Pérez and Hugo R. Arias


DOI: 10.2174/1381612822666160127112021




Nicotinic Acetylcholine Receptors in the Pathophysiology of Al zheimer’s Disease: The Role of Protein-Protein Interactions in Current and Future Treatment

, 22(14): 2015 - 2034

Morten Skøtt Thomsen, Jesper Tobias Andreasen, Maria Arvaniti and Kristi Anne Kohlmeier


DOI: 10.2174/1381612822666160127112357




The Role of α7 Nicotinic Acetylcholine Receptors and α7-Specific Antibodies in Neuroinflammation Related to Alzheimer Disease

, 22(14): 2035 - 2049

Maryna Skok and Olena Lykhmus


DOI: 10.2174/1381612822666160127112914




Promising Therapies for Alzheimer's Disease

, 22(14): 2050 - 2056

Annamaria Confaloni, Giuseppe Tosto and Ada Maria Tata


DOI: 10.2174/1381612822666160215154218




Desformylflustrabromine: A Novel Positive Allosteric Modulator for beta2 Subunit Containing Nicotinic Receptor Sub-Types

, 22(14): 2057 - 2063

Anshul A. Pandya


DOI: 10.2174/1381612822666160127113159




Serotonergic Drugs: Agonists/Antagonists at Specific Serotonergic Subreceptors for the Treatment of Cognitive, Depressant and Psychotic Symptoms in Alzheimer’s Disease

, 22(14): 2064 - 2071

Felix-Martin Werner and Rafael Covenas


DOI: 10.2174/1381612822666160127113524




Targeting the Cholinergic System for Neuroprotection and/or Enhancement of Functional Recovery Following Neurotrauma

, 22(14): 2072 - 2082

Kathleen B.G. Huber, Victor V. Uteshev and James R. Pauly


DOI: 10.2174/1381612822666160127113631




The Cholinergic Potential, the Vagus Nerve and Challenges in Treatment of Traumatic Brain Injury

, 22(14): 2083 - 2092

Victor V. Uteshev, Olli Tenovuo and Nikhil Gaidhani


DOI: 10.2174/1381612822666160127111630




Serotonergic and Cholinergic Strategies as Potential Targets for the Treatment of Schizophrenia

, 22(14): 2093 - 2116

Agnieszka Nikiforuk


DOI: 10.2174/1381612822666160127113758




Targeting Functional Biomarkers in Schizophrenia with Neuroimaging

, 22(14): 2117 - 2123

Korey P. Wylie, Jason Smucny, Kristina T. Legget and Jason R. Tregellas


DOI: 10.2174/1381612822666160127113912




The Cholinergic System: An Emerging Drug Target for Schizophrenia

, 22(14): 2124 - 2133

Andrew Gibbons and Brian Dean


DOI: 10.2174/1381612822666160127114010




The Recent Development of α7 Nicotinic Acetylcholine Receptor (nAChR) Ligands as Therapeutic Candidates for the Treatment of Central Nervous System (CNS) Diseases

, 22(14): 2134 - 2151

Corinne Beinat, Samuel D. Banister, Marco Herrera and Michael Kassiou


DOI: 10.2174/1381612822666160127114125




Cholinergic Targets in Lung Cancer

, 22(14): 2152 - 2159

Eliot R. Spindel


DOI: 10.2174/1381612822666160127114237




Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment

, 22(14): 2160 - 2169

Vanessa Mucchietto, Arianna Crespi, Francesca Fasoli, Francesco Clementi and Cecilia Gotti


DOI: 10.2174/1381612822666160203144114




Muscarinic Receptors as Targets for Metronomic Therapy in Breast Cancer

, 22(14): 2170 - 2177

María Elena Sales


DOI: 10.2174/1381612822666160229115317




Neuroprotective Strategies in Glaucoma

, 22(14): 2178 - 2192

Cynthia A. Gossman, John Christie, Mark K. Webster, David M. Linn and Cindy L. Linn


DOI: 10.2174/1381612822666160128144747




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