Contents

Current Pharmaceutical Design, Volume 20 - Number 5

Editorial (Thematic Issue: Structure-Based Drug Design: Strategies and Challenges)

, 20(5): 685 - 686

Guang-Fu Yang


DOI: 10.2174/138161282005140214161643




Structure-Based Drug Design to Overcome Drug Resistance: Challenges and Opportunities

, 20(5): 687 - 693

Rafaela S. Ferreira and Adriano D. Andricopulo


DOI: 10.2174/138161282005140214161949




Resistance Mutations Against HCV Protease Inhibitors and Antiviral Drug Design

, 20(5): 694 - 703

Luqing Shang, Kai Lin and Zheng Yin


DOI: 10.2174/13816128113199990008




Structural Basis of Resistance to Anti-Cytochrome bc1 Complex Inhibitors: Implication for Drug Improvement

, 20(5): 704 - 724

Lothar Esser, Chang-An Yu and Di Xia


DOI: 10.2174/138161282005140214163327




Structure-based Design of Conformationally Flexible Reverse Transcriptase Inhibitors to Combat Resistant HIV

, 20(5): 725 - 739

Ge-Fei Hao, Sheng-Gang Yang and Guang-Fu Yang


DOI: 10.2174/138161282005140214163439




Acetohydroxyacid Synthase: A Target for Antimicrobial Drug Discovery

, 20(5): 740 - 753

Nason Pue and Luke W. Guddat


DOI: 10.2174/13816128113199990009




Structural Insights into Chitinolytic Enzymes and Inhibition Mechanisms of Selective Inhibitors

, 20(5): 754 - 770

Tian Liu, Lei Chen, Qiang Ma, Xu Shen and Qing Yang


DOI: 10.2174/138161282005140214164730




Therapeutic Peptides: New Arsenal Against Drug Resistant Pathogens

, 20(5): 771 - 792

Wendy W. K. Mok and Yingfu Li


DOI: 10.2174/13816128113199990011




ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development

, 20(5): 793 - 807

Young Hee Choi and Ai-Ming Yu


DOI: 10.2174/138161282005140214165212




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