Contents

Current Pharmaceutical Design, Volume 20 - Number 2

Editorial (Thematic Issue: Mitochondria and Subcellular Organelles as Treatment Targets Against Pathological Conditions)

, 20(2): 153 - 154

Antonio Toninello


DOI: 10.2174/13816128113199990038




Hydrogen Peroxide Produced by Mitochondrial Monoamine Oxidase Catalysis: Biological Implications

, 20(2): 155 - 160

Dale E. Edmondson


DOI: 10.2174/13816128113190990406




Effects of Novel Monoamine Oxidases and Cholinesterases Targeting Compounds on Brain Neurotransmitters and Behavior in Rat Model of Vascular Dementia

, 20(2): 161 - 171

Anna Stasiak, Miroslaw Mussur, Mercedes Unzeta, Abdelouahid Samadi, Jose L. Marco-Contelles and W. Agnieszka Fogel


DOI: 10.2174/13816128113199990026




Mitochondria-targeted Resveratrol Derivatives Act as Cytotoxic Pro-oxidants

, 20(2): 172 - 179

Nicola Sassi, Andrea Mattarei, Michele Azzolini, Paolo Bernardi, Ildiko' Szabo', Cristina Paradisi, Mario Zoratti and Lucia Biasutto


DOI: 10.2174/13816128113199990034




CDK Inhibitors Induce Mitochondria-mediated Apoptosis Through the Activation of Polyamine Catabolic Pathway in LNCaP, DU145 and PC3 Prostate Cancer Cells

, 20(2): 180 - 188

Elif Damla Arisan, Pinar Obakan, Ajda Coker-Gurkan, Annarica Calcabrini, Enzo Agostinelli and Narcin Palavan Unsal


DOI: 10.2174/13816128113199990029




Correlation between Potassium Channel Expression and Sensitivity to Drug-induced Cell Death in Tumor Cell Lines

, 20(2): 189 - 200

Luigi Leanza, Paul O’Reilly, Anne Doyle, Elisa Venturini, Mario Zoratti, Eva Szegezdi and Ildiko Szabo


DOI: 10.2174/13816128113199990032




Cancer Therapy: Targeting Mitochondria and other Sub-cellular Organelles

, 20(2): 201 - 222

Obinna C. Ubah and Heather M. Wallace


DOI: 10.2174/13816128113199990031




Mitochondrial Permeability Transition as Target of Anticancer Drugs

, 20(2): 223 - 244

Lisa Dalla Via, Aida N. Garcia-Argaez, Mariano Martinez-Vazquez, Silvia Grancara, Pamela Martinis and Antonio Toninello


DOI: 10.2174/13816128113199990033




A Novel Assay Platform for the Detection of Translation Modulators of Spermidine/ Spermine Acetyltransferase

, 20(2): 245 - 252

Oscar Perez-Leal, Magid Abou-Gharbia, John Gordon, Wayne E. Childers and Salim Merali


DOI: 10.2174/13816128113199990035




An Eudesman Derivative from Verbesina persicifolia D.C. as a Natural Mild Uncoupler in Liver Mitochondria. A New Potential Anti-obesity Agent?

, 20(2): 253 - 261

Lisa Dalla Via, Aida N. Garcia-Argaez, Alessandra Braga, Mariano Martinez-Vazquez, Silvia Grancara, Pamela Martinis, Enzo Agostinelli and Antonio Toninello


DOI: 10.2174/13816128113199990028




Charge Deficient Analogues of the Natural Polyamines

, 20(2): 262 - 277

Janne Weisell, Mervi T. Hyvonen, Leena Alhonen, Jouko Vepsalainen, Tuomo A. Keinanen and Alex R. Khomutov


DOI: 10.2174/13816128113199990037




RNAi in Plasmodium

, 20(2): 278 - 283

Ann-Kristin Mueller, Christiane Hammerschmidt-Kamper and Annette Kaiser


DOI: 10.2174/13816128113199990027




Hypusine Modification of the Ribosome-binding Protein eIF5A, a Target for New Anti-Inflammatory Drugs: Understanding the Action of the Inhibitor GC7 on a Murine Macrophage Cell Line

, 20(2): 284 - 292

Oedem Paulo de Almeida Jr, Thais Regina Toledo, Danuza Rossi, Daniella de Barros Rossetto, Tatiana Faria Watanabe, Fabio Carrilho Galvao, Alexandra Ivo Medeiros, Cleslei Fernando Zanelli and Sandro Roberto Valentini


DOI: 10.2174/13816128113199990036




Biocomputational Resources Useful For Drug Discovery Against Compartmentalized Targets

, 20(2): 293 - 300

Francisca Sanchez-Jimenez, Armando Reyes-Palomares, Aurelio A. Moya-Garcia, Juan AG Ranea and Miguel Angel Medina


DOI: 10.2174/13816128113199990030




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