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Current Pharmaceutical Design, Volume 19 - Number 5

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: Current Status and Future Perspectives in the Development of Novel Irreversible Inhibitors for the Treatment of Mutant Non-small Cell Lung Cancer

, 19(5): 818 - 832

Elena Galvani, Roberta Alfieri, Elisa Giovannetti, Andrea Cavazzoni, Silvia La Monica, Maricla Galetti, Claudia Fumarola, Mara Bonelli, Marco Mor, Marcello Tiseo, Godefridus J. Peters, Pier Giorgio Petronini and Andrea Ardizzoni

DOI: 10.2174/1381612811306050818

Detection and Therapeutic Implications of c-Met Mutations in Small Cell Lung Cancer and Neuroendocrine Tumors

, 19(5): 833 - 840

J. Voortman, T. Harada, R.P. Chang, J.K. Killian, M. Suuriniemi, W.I. Smith, P.S. Meltzer, M. Lucchi, Y. Wang and G. Giaccone

DOI: 10.2174/1381612811306050833

Synergistic Antiproliferative and Antiangiogenic Effects of EGFR and mTOR Inhibitors

, 19(5): 918 - 926

L. Porcelli, A.E. Quatrale, P. Mantuano, N. Silvestris, J.F. Rolland, L. Biancolillo, A. Paradiso and A. Azzariti

DOI: 10.2174/1381612811306050918

Enhancement of the Antiproliferative Activity of Gemcitabine by Modulation of c-Met Pathway in Pancreatic Cancer

, 19(5): 940 - 950

Amir Avan, Karl Quint, Francesco Nicolini, Niccola Funel, Adam E. Frampton, Mina Maftouh, Serena Pelliccioni, Gerrit J. Schuurhuis, Godefridus J. Peters and Elisa Giovannetti

DOI: 10.2174/1381612811306050940

Targeting the Akt-pathway to Improve Radiosensitivity in Glioblastoma

, 19(5): 951 - 957

Ravi S. Narayan, Carlos Alexandre Fedrigo, Lukas J.A. Stalpers, Brigitta G. Baumert and Peter Sminia

DOI: 10.2174/1381612811306050951

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